摘要
斑马鱼作为一种新型的模式动物,因其个体小、发育周期短和透明易观察等优点,已在发育生物学、遗传学、基础医学、药理学、毒理学、药物研发以及生态环境评价等诸多领域得到了广泛应用,并且随着功能性食品、营养品和天然化妆产品的需求不断增加。斑马鱼已经是一种实用工具,可有效鉴别天然产品中的有效物质。近年来,作为国际公认的新型脊椎类模型动物,斑马鱼已用于多种植物多糖及产品的抗氧化、免疫调节及心脏保护等生物活性评价。本文将介绍近年来斑马鱼作为模式动物在多糖,特别是植物多糖生物活性研究的进展。
Being a new model animal,zebrafish has been widely used in many fields such as developmental biology,genetics,basic medicine,pharmacology and toxicology,drug development,and ecological environment evaluation because of its small size,short developmental cycle and transparency for easy observation.And with the increasing demand for functional foods,nutritional products,and natural cosmetic products,zebrafish has been a practical tool to effectively identify the active substances in natural products.In recent years,as a new internationally recognized vertebrate model animal,zebrafish have been used for the evaluation of biological activities such as antioxidant,immunomodulation,and cardioprotection of various plant polysaccharides and products.In this paper,we will introduce the progress of zebrafish as a model animal in the study of polysaccharides,especially plant polysaccharide bioactivity in recent years.
作者
尹娜
陈秋燕
王瑞芳
齐景伟
王园
YIN Na;CHEN Qiuyan;WANG Ruifang;QI Jingwei;WANG Yuan(College of Animal Sciences,Inner Mongolia Agricultural University,Hohhot 010018,China;Inner Mongolia Herbivorous Livestock Feed Engineering Technology Research Center,Hohhot 010018)
出处
《中国实验动物学报》
CAS
CSCD
北大核心
2022年第5期705-712,共8页
Acta Laboratorium Animalis Scientia Sinica
基金
内蒙古自然科学基金项目(2020MS03041)
内蒙古自治区关键技术攻关计划项目(2020GG0030)
内蒙古农业大学科技成果转化专项资金(YZGC2017025)
内蒙古自治区科技重大专项(2020ZD0004)。
关键词
斑马鱼
植物多糖
生物活性
zebrafish
plant polysaccharides
bioactivity
作者简介
尹娜(1997-),女,博士,研究方向:生物饲料的研发与应用。Email:yinna0420@163.com;通信作者:王园(1986-),女,博士,副教授,研究方向:生物饲料的研发与应用。Email:wangyuan.926@163.com。
