摘要
目的利用实时剪切波弹性呈像(SWE)和彩色脉搏波成像(UFPWV)技术定量分析2型糖尿病(T2DM)患者颈总动脉血管壁的弹性范围,评价2种超声成像技术在T2DM患者颈总动脉血管壁硬度方面的应用价值。方法选取云南大学附属医院经临床确诊的T2DM患者(T2DM组)及健康体检者(健康组)各100例,每组按年龄再分为3组(<45岁、45~59岁、>59岁),SWE及UFPWV技术获得所有受检者颈总动脉血管壁的杨氏模量值(Max、Min、Mean)及脉搏波速度(PWV),包括收缩期开始时的脉搏波速度(PWVBS)、收缩期结束时的脉搏波速度(PWVES),得到颈总动脉血管壁的纵向及环向硬度。结果T2DM组患者颈总动脉血管壁各杨氏模量值(Max、Min、Mean)、PWV(PWVBS、PWVES)均大于健康组受检者(P<0.05)。T2DM组男、女性颈总动脉血管壁各杨氏模量值(Max、Min、Mean)、PWV(PWVBS、PWVES)差异均无统计学意义(P>0.05)。T2DM组患者各杨氏模量值(Max、Min、Mean)、PWV(PWVBS、PWVES)均与年龄呈正相关(r=0.776、0.706,P<0.05)。结论SWE及UFPWV成像技术可以评价颈总动脉血管壁的纵向及环向硬度,T2DM患者颈总动脉血管壁的纵向及环向硬度高于健康人。2种超声技术综合分析对提高早期发现动脉硬化和测量总动脉血管壁硬度的准确性有重要价值。
Objective To quantitatively analyze the elastic range of vascular wall of the common carotid artery in the patients with type 2 diabetes mellitus(T2DM)by using real-time shear wave elastrography(SWE)and ultrafast pulse wave velocity(UFPWV)techniques,and to evaluate their application value in the common carotid arterial vascular wall hardness of T2DM.Methods One hundred patients with clinically diagnosed T2DM(T2DM group)and 100 healthy subjects undergoing physical examination(health group)in Affiliated Hospital of Yunnan University were selected and divided into 3 groups(<45 years old,45-59 years old,>59 years old)according to age.The Young’s modulus values(Max,Min,Mean),pulse ware velocity(PWV)which contained PWVBS,PWVES,in all subjects were obtained by SWE and UFPWV technologies,the longitudinal and circumferential vessel wall stiffness of the common carotid arterial vascular wall were obtained.Results The Young’s modulus values(Max,Min,Mean),PWV(PWVBS,PWVES),longitudinal and circumferential vessel wall stiffness of common carotid artery in the T2DM group were greater than those in the health group(P<0.05).There was no statistical differences in the Young’s modulus values of(Max,Min,Mean),PWV(PWVBS,PWVES)of the common carotid artery between males and females in the T2DM group(P>0.05).The Young’s modulus values(Max,Min,Mean),PWV(PWVBS,PWVE)in the T2DM group were all positively correlated with the age(r=0.776,0.706,P<0.05).Conclusion The SWE and UFPWV imaging techniques could evaluate the longitudinal and circumferential stiffness of the common carotid artery.The longitudinal and circumferential stiffnesses of the common carotid artery in T2DM patients are higher than those in the health people.Comprehensive analysis of the two ultrasound techniques is of great value in accuracy for early finding arteriosclerosis and measuring vascular wall hardness of common carotid artery.
作者
谭丽莉
徐帆
孙月
杨寒凝
陆永萍
TAN Lili;XU Fan;SUN Yue;YANG Hanning;LU Yongping(Graduate School of Kunming Medical University,Kungming,Yunnan 650300,China;Department of Ultrasound,Affiliated Hospital of Yunnan University,Kunming,Yunnan 650021,China)
出处
《重庆医学》
CAS
2022年第21期3634-3638,3643,共6页
Chongqing medicine
基金
云南省“万人计划”名医专项(YNWR-MY-2018-004)
云南省医学领军人才培养基金项目(L-201616)。
关键词
2型糖尿病
颈总动脉
血管壁硬度
剪切波弹性成像
彩色脉搏波成像
type 2 diabetes mellitus
common carotid artery
hardness of vascular wall
shear wave elastrography
ultrafast pulse wave velocity
作者简介
谭丽莉(1997-),在读硕士研究生,本科,主要从事心血管超声医学研究;通信作者:陆永萍,E-mail:luyongp@163.com。
