摘要
目的 探讨心血管内科对急性心绞痛患者使用氯吡格雷的临床治疗效果。方法 选择2018年7月—2019年7月沂水县人民医院心血管内科收治的112例急性心绞痛患者作为研究对象,依照数字随机法平均分成对照组(n=56,采取常规治疗方案)和研究组(n=56,在常规治疗方案的基础上增加氯吡格雷),比较两组患者治疗效果、每日心绞痛发作次数以及每次心绞痛发作时持续时间变化情况、胆固醇以及血压变化情况。结果研究组患者的治疗有效率达96.43%,明显高于对照组的83.93%,差异有统计学意义(χ^(2)=4.940,P=0.026);治疗前两组患者每日心绞痛发作次数和每次发作时持续时间对比,差异无统计学意义(P>0.05);治疗后研究组患者每日心绞痛发作次数和每次发作时持续时间均比对照组要少(短),差异有统计学意义(P<0.05);治疗前两组患者胆固醇以及血压检测结果对比差异无统计学意义(P>0.05),治疗后研究组患者两项指标检测结果均明显优于对照组,差异有统计学意义(P<0.05)。结论 对急性心绞痛发作的患者在常规治疗的基础上增加氯吡格雷能够显著提升其治疗效果、降低心绞痛发作次数和持续时间、改善血脂和血压水平,具有较高的应用价值。
Objective To investigate the clinical effect of clopidogrel in patients with acute angina pectoris in cardiovascular medicine.Methods A total of 112 patients with acute angina pectoris admitted to the Department of Cardiovascular Medicine of Yishui County People’s Hospital from July 2018 to July 2019 were selected as the research subjects,and were equally divided into the control group(n=56,taking conventional treatment) and the stady group according to the numerical random method(n=56,clopidogrel was added to the usual regimen).The treatment effect,daily number of angina pectoris attacks,changes in duration of each angina pectoris attack,changes in cholesterol and blood pressure were compared between the two groups.Results The treatment effective rate of the patients in the study group was 96.43%,which was significantly higher than 83.93% in the control group,and the difference was statistically significant(χ^(2)=4.940,P=0.026).There was no statistically significant difference in the number of daily angina pectoris attacks and the duration of each attack between the two groups before treatment(P>0.05).After treatment,the number of daily angina attacks and the duration of each attack in the study group were less(shorter) than those in the control group,the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in the test results of cholesterol and blood pressure between the two groups(P>0.05),and the test results of the two indicators in the study group after treatment were significantly better than those in the control group,the difference was statistically significant(P<0.05).Conclusion For patients with acute angina pectoris,adding clopidogrel on the basis of conventional treatment can significantly improve the therapeutic effect,reduce the number and duration of angina pectoris attacks,and improve their blood lipid and blood pressure levels,which has high application value.
作者
邵明凤
SHAO Mingfeng(Department of Cardiology,Yishui People's Hospital,Linyi,Shandong Province,276000 China)
出处
《系统医学》
2022年第14期103-106,共4页
Systems Medicine
关键词
心血管内科
急性心绞痛
临床疗效
氯吡格雷
Cardiovascular medicine
Acute angina pectoris
Clinical efficacy
Clopidogrel
作者简介
邵明凤(1968-),女,本科,副主任医师,研究方向为心血管内科临床。
