摘要
目的 探究宫缩乏力性产后出血实施卡前列甲酯栓治疗的临床效果。方法 随机纳入2017年1月-2019年12月时段内60例宫缩乏力性产后出血产妇并予以分组,采纳常规宫缩素治疗的30例样本(列入对照组),采纳卡前列甲酯栓的30例样本(列入观察组),对比指标:第三产程时间、产后血红蛋白下降量、术中及产后出血情况、不良反应率。结果 治疗总有效率比较,观察组明显高于对照组(P<0.05);观察组较对照组患者而言,第三产程时间更短,产后24h血红蛋白下降量更低,组间对比差异均存在统计学意义(P<0.05);两组术中出血量、产后2h、产后24h出血量对比,观察组均明显低于对照组(P<0.05);止血时间及血性恶露持续时间均短于对照组(P<0.05);两组患者不良反应发生率比较(6.67% VS 16.67%),观察组略低于对照组,但组间差异无统计学意义(P>0.05)。结论 应用卡前列甲酯栓治疗宫缩乏力性产后出血患者可发挥显著止血效果,有效减少术中、术后出血量,同时不良反应风险小,安全性高。
Objective To explore the clinical effect of carboprost methyl ester suppository in the treatment of uterine asthenia postpartum hemorrhage.Methods 60 pregnant women with uterine asthenia postpartum hemorrhage from January 2017 to December 2019 were randomLy included and divided into groups.30 samples treated with conventional oxytocin (included in the control group) and 30 samples treated with carboprost methyl suppository (included in the observation group).Comparison indexes:time of the third stage of labor,decrease of postpartum hemoglobin,intraoperative and postpartum hemorrhage Adverse reaction rate.Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05);Compared with the control group,the time of the third stage of labor in the observation group was shorter and the decrease of hemoglobin 24 hours after delivery was lower.There was significant difference between the two groups (P<0.05);The amount of intraoperative bleeding,2 hours postpartum and 24 hours postpartum bleeding in the observation group were significantly lower than those in the control group (P<0.05);The hemostasis time and the duration of bloody lochia in the control group were shorter than those in the control group (P<0.05);The incidence of adverse reactions in the observation group was slightly lower than that in the control group (6.67% vs 16.67%),but there was no significant difference between the two groups (P>0.05).Conclusion Carboprost methyl ester suppository can play a significant hemostatic effect in the treatment of patients with uterine asthenia postpartum hemorrhage,effectively reduce the amount of intraoperative and postoperative bleeding,with low risk of adverse reactions and high safety.
作者
吴艳华
WU Yanhua(Department of Pharmacy,Shenzhen Luohu Maternal and Child Health Hospital,Shenzhen,Guangdong,518019)
出处
《智慧健康》
2022年第14期108-110,共3页
Smart Healthcare
关键词
宫缩乏力性产后出血
卡前列甲酯栓
止血效果
Uterine asthenia postpartum hemorrhage
Carboprost methyl ester suppository
Hemostatic effect
