摘要
椎基底动脉延长扩张症(vertebrobasilar dolichoectasia,VBD)是脑血管病的一种,主要表现为椎动脉和/或基底动脉的异常扩张迂曲,属于向外的营养不良重构。由于椎基底动脉所处位置空间狭小,供血区包含多个重要中枢,其过度迂曲扩张将产生较为严重的后果。目前关于VBD病因的研究较少,近期的研究结果表明炎症、血流动力学等参与了VBD病变血管重构,进一步导致VBD的发生发展。本文现围绕VBD血管重构相关病因的研究进展进行综述,以期为VBD发生发展机制方面的研究提供新思路并为相关治疗研究提供新方向。
Vertebrobasilar dolichoectasia(VBD)is a kind of cerebrovascular disease,mainly manifested as abnormal dilation and tortuality of vertebral artery and/or basilar artery,which belongs to outward hypotrophic remodeling.Due to the narrow location of vertebrobasilar artery,the blood supply area contains several important centers,and its excessive tortuous expansion will produce serious consequences.Currently,there are few studies on the etiology of VBD.Recent research results indicate that inflammation and hemodynamics,for example,are involved in vascular remodeling in VBD,further leading to the occurrence and development of VBD.This paper reviews the research progress on the etiology of vascular remodeling in VBD,in order to provide new ideas for the study on the pathogenesis of VBD and new directions for the treatment of VBD.
作者
束宁德
赵洋
刘庆新
SHU Ningde;ZHAO Yang;LIU Qingxin(Binzhou Medical University Hospital,Binzhou 256603,China;不详)
出处
《中国医学创新》
CAS
2022年第18期173-176,共4页
Medical Innovation of China
基金
山东省医药卫生科技发展计划项目(2017WS157)
滨州医学院科技计划项目(BY2019KJ07)。
关键词
椎基底动脉延长扩张症
血管重构
病因
Vertebrobasilar dolichoectasia
Vascular remodeling
Etiology
作者简介
通信作者:刘庆新。
