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硝普钠联合多巴胺治疗急性心力衰竭患者的临床效果观察 被引量:2

Clinical effect of sodium nitroprusside combined with dopamine in the treatment of patients with acute heart failure
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摘要 目的研究对急性心力衰竭(心衰)患者实施硝普钠联合多巴胺治疗的临床效果。方法58例急性心衰患者,将其随机分为研究组和参照组,每组29例。参照组给予硝普钠治疗,研究组在参照组基础上采用多巴胺治疗。比较两组患者治疗后的临床效果、心功能指标。结果研究组治疗总有效率93.10%高于参照组的68.97%,差异具有统计学意义(P<0.05)。治疗后,研究组左室收缩末期内径(LVESD)(36.70±2.21)mm、左室舒张末期内径(LVEDD)(46.47±3.22)mm、左室射血分数(LVEF)(49.77±3.98)%优于参照组的(41.69±2.61)mm、(50.48±4.36)mm、(43.75±4.09)%,差异均具有统计学意义(P<0.05)。结论针对急性心衰患者采取硝普钠联合多巴胺治疗干预,患者临床效果及心功能指标显著改善,疗效佳,适于推广与应用。 Objective To study the clinical effect of sodium nitroprusside combined with dopamine in the treatment of patients with acute heart failure.Methods A total of 58 patients with acute heart failure were randomly divided into research group and reference group,with 29 cases in each group.The reference group was treated with sodium nitroprusside,and the research group was treated with dopamine on the basis of the reference group.The clinical effects and cardiac function indexes of the two groups after treatment were compared.Results The total effective rate of treatment in the research group was 93.10%,which was higher than 68.97%in the reference group,and the difference was statistically significant(P<0.05).After treatment,the left ventricular end systolic diameter(LVESD)(36.70±2.21)mm,left ventricular end diastolic diameter(LVEDD)(46.47±3.22)mm,and left ventricular ejection fraction(LVEF)(49.77±3.98)%of the research group were better than(41.69±2.61)mm,(50.48±4.36)mm,and(43.75±4.09)%of the reference group,and the difference was statistically significant(P<0.05).Conclusion The therapeutic intervention of sodium nitroprusside combined with dopamine in patients with acute heart failure can significantly improve the clinical effect and cardiac function indexes of patients with good efficacy,which is suitable for promotion and application.
作者 王超 WANG Chao(Traditional Chinese Medicine Hospital of Kazuo County,Chaoyang 122300,China)
出处 《中国实用医药》 2022年第8期117-119,共3页 China Practical Medicine
关键词 硝普钠 多巴胺 急性心力衰竭 临床效果 Sodium nitroprusside Dopamine Acute heart failure Clinical effect
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