摘要
目的分析介入栓塞术(IE)联合尼莫地平治疗动脉瘤性蛛网膜下腔出血(aSAH)的临床效果。方法选取2018年1月至2019年10月我院收治的135例aSAH患者,根据治疗方法不同分为观察组(n=67)和对照组(n=68)。对照组仅采用IE治疗,观察组采用IE联合尼莫地平治疗,比较两组的血清炎性因子水平及短期预后。结果治疗2周后,观察组的血清IL-8、VEGF、TNF-α水平均低于对照组(P<0.05).治疗2周后,观察组的GOS评分优于对照组(P<0.05).结论IE联合尼莫地平治疗aSAH的效果显著,可有效减轻患者的炎性反应,改善短期预后。
Objective To analyze the clinical effect of interventional embolization(EE)combined with nimodipine in the treatment of aneurysmal subarachnoid hemorrhage(aSAH).Methods 135 aSAH patients admitted to our hospital from January 2018 to October 2019 were selected and divided into observation group(n=67)and control group(n=68)according to different treatment methods.The control group was only treated with IE,and the observation group was treated with IE combined with nimodipine.The serum inflammatory factor levels and short-term prognosis were compared between the two groups.Results After 2 weeks of treatment,the serum IL-8,VEGF and TNF-α levels of the observation group were lower than those of the control group(P<0.05).After 2 weeks of treatment,the GOS score of the observation group was better than that of the control group(P<0.05).Conclusions EE combined with nimodipine has significant effect in the treatment of aSAH,which can effectively reduce the inflammatory response of patients,and improve the short-temi prognosis.
作者
刘艳
牛金霞
耿灵敏
LIU Yan;NIU Jinxia;GENG Lingmin(Department of Neurology,Wen County People's Hospital,Jiaozuo 454150,China)
出处
《临床医学工程》
2022年第3期323-324,共2页
Clinical Medicine & Engineering
基金
河南省医学科技攻关计划联合共建项目(项目编号:LHGJ20191472)。
关键词
动脉瘤性蛛网膜下腔出血
介入栓塞术
尼莫地平
Aneurysmal subarachnoid hemorrhage
Interventional embolization
Nimodipine
作者简介
刘艳(1982-),女,河南焦作人,本科学历,副主任医师,研究方向:神经内科疾病。
