摘要
目的探究丁苯酞软胶囊联合依达拉奉治疗脑梗死的临床应用效果。方法选取2018年4月至2020年6月于鞍山市肿瘤医院收治的100例脑梗死患者作为研究对象,按照计算机随机分配法分为对照组(50例)与实验组(50例)。对照组患者采用依达拉奉进行治疗,实验组采用丁苯酞软胶囊联合依达拉奉进行治疗,比较两组患者治疗后的临床疗效、不良反应总发生率、Barthel指数及生活质量。结果实验组的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。实验组的Barthel指数高于对照组,差异有统计学意义(P<0.05)。实验组的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。实验组的心理功能、物质功能、社会功能、躯体功能评分高于对照组,差异有统计学意义(P<0.05)。结论丁苯酞软胶囊联合依达拉奉治疗脑梗死的临床效果显著,可有效改善患者的生活质量,减少其不良反应。
Objective To investigate the clinical application effect of Butylphthalide Soft Capsules combined with Edaravone in treatment of cerebral infarction.Methods A total of 100 patients with cerebral infarction who were treated in Anshan Tumor Hospital from April 2018 to June 2020 were selected as the research objects.According to the computer random assignment method,the patients were assigned and divided into the control group(50 patients)and the experimental group(50 patients).The control group was treated with Edaravone,and the experimental group was treated with Butylphthalide Soft Capsules combined with Edaravone.The clinical efficacy,total incidence of adverse reactions,Barthel index and quality of life of the two groups were compared after treatment.Results The total effective rate of treatment of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).The Barthel index of the experimental group was higher than that of the control group,with statistical significance(P<0.05).The total incidence of adverse reactions in the experimental group was lower than that in the control group,the difference was statistically significant(P<0.05).The scores of psychological function,material function,social function and physical function in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The clinical efficacy of Butylphthalide Soft Capsules combined with Edaravone in the treatment of cerebral infarction is significant,which can effectively improve the quality of life of patients and reduce their adverse reactions.
作者
安娜
AN Na(The Second Medical Ward,Anshan Tumor Hospital,Liaoning Province,Anshan114034,China)
出处
《中国当代医药》
CAS
2022年第2期52-54,共3页
China Modern Medicine
关键词
丁苯酞软胶囊
依达拉奉
脑梗死
临床效果
Butylphthalide Soft Capsules
Edaravone
Cerebral infarction
Clinical effect
