摘要
代谢相关脂肪性肝病(metabolic associated fatty liver disease,MAFLD)是作为描述这种疾病的一个更合适的总括述语,新的定义将代谢功能障碍列为肝病的重要病因,论证了MAFLD的高异质性,加快了向新治疗的转化路径.MAFLD的肝外并发症其发生率和相关疾病,远远超过肝病本身,严重威脅着人类健康.鉴于当前人们对其严重性认识不足,且对肝外并发病的疾病范围、发病机制、诊断的研究还不完善,尤其当前对其缺乏有效的药物治疗,有鉴于此本文就MAFLD肝外并发症研究现状与进展作一介绍与述评,与广大读者共享.
Metabolic associated fatty liver disease(MAFLD)is a more appropriate general predicate to describe non-alcoholic fatty liver disease.The new definition lists metabolic dysfunction as an important cause of liver disease,demonstrates the high heterogeneity of this condition,and speeds up the transformation path to new treatment.The incidence of extrahepatic complications and related diseases of MAFLD far exceed that of the liver disease itself,which seriously threatens human health.In view of the current insufficient understanding of its severity,and the imperfect understanding of the disease scope,pathogenesis,and diagnosis of extrahepatic complications,especially the lack of effective drug treatment,this paper introduces and reviews the research status and progress of extrahepatic complications of MAFLD.
作者
池肇春
Zhao-Chun Chi(Department of Gastroenterology,Qingdao Municipal Hospital,Qingdao 266011,Shandong Province,China)
出处
《世界华人消化杂志》
CAS
2022年第1期1-16,共16页
World Chinese Journal of Digestology
关键词
非酒精性脂肪性肝病
代谢相关脂肪性肝病
肝外并发症
Nonalcoholic fatty liver disease
Metabolic associated fatty liver disease
Extrahepatic complications
作者简介
通讯作者:池肇春,教授,主任医师,主要从事肝病的临床研究.266011,山东省青岛市胶州路1号,青岛市市立医院消化内科.czchow123@163.com。
