摘要
目的分析2016—2020年广东省消除艾滋病、梅毒和乙肝母婴传播(简称"消除母婴传播")的效果,为进一步推进广东省消除母婴传播工作提供依据。方法计算2016—2020年广东省孕产妇艾滋病、梅毒和乙肝相关指标的构成比和率,并使用趋势χ^(2)检验分析各年度间构成比和率的变化趋势。结果2016—2020年,广东省分娩产妇累计8575890例,孕产妇HIV、梅毒和乙肝检测率约99.81%,艾滋病感染孕产妇抗病毒药物应用比例占88.13%(1389/1576),艾滋病暴露儿童抗病毒药物应用比例占95.32%(1507/1581),梅毒感染孕产妇接受治疗比例占91.43%(13960/15269),梅毒暴露儿童接受治疗比例占82.72%(10596/12810),乙肝暴露儿童免疫球蛋白接种率占99.67%(817172/819858),5岁内儿童乙肝表面抗原(HBsAg)检测阳性率0.83/万;2016—2020年HIV母婴传播率2.99%,未达标消除艾滋病母婴传播目标要求,对比各年间HIV母婴传播率2016年最高为4.92%,2019年最低约1.67%,呈逐年下降趋势,2020年又波动至2.84%,指标波动较明显;先天梅毒发病率11/10万,乙肝母婴传播率0.35%,对比各年间均已达标消除梅毒和乙肝母婴传播目标要求。结论2016—2020年广东省消除艾滋病、梅毒和乙肝母婴传播过程指标和效果指标相比世界卫生组织消除母婴传播消除认证指标还有少许差距,但干预指标取得了一定的效果,需要进一步加强干预措施,争取进一步消除消除艾滋病、梅毒和乙肝的母婴传播。
Objective To analyze the effect of eliminating mother-to-child transmission(EMTCT)of AIDS,syphilis and hepatitis B in Guangdong Province during 2016 to 2020,and to provide basis for further promoting the elimination of mother-to-child transmission in Guangdong.Methods The proportions and rates of the indicators related to AIDS,syphilis and hepatitis B infection among pregnant women in Guangdong province from 2016 to 2020 were calculated,and trend 2 test was used to analyze the changing trends of proportions and rates.Results The number of puerperae in Guangdong province was 8575890 from 2016 to 2020.The total detection rate of HIV,syphilis and hepatitis B was about 99.81%.The proportion of utilization of antiviral drugs for pregnant women and puerperae with HIV positive was 88.13%(1389/1576)and the proportion of utilization of antiviral drugs for children with HIV positive was 95.32%(1507/1581).The proportion of pregnant women and puerperae receiving medical treatment for syphilis was 91.43%(13960/15269)and the proportion of children receiving medical treatment for syphilis were 82.72%(10596/12810).The inoculation rate of immune globulin for children with hepatitis B virus was 99.67%(817172/819858)and the positive rate of hepatitis B surface antigen(HBsAg)among children under 5 years old was 0.83/10000.The mother-to-child transmission rate of HIV was 2.99%from 2016 to 2020,which failed to achieve the goal for eliminating mother-to-child transmission of AIDS.The highest mother-to-child transmission rate of HIV was 4.92%in 2016 while the lowest mother-to-child transmission rate of HIV was 1.67%in 2019.With decreased tendency from 2016 to 2020,the mother-to-child transmission rate of HIV reached 2.84%in 2020.The incidence rate of congenital syphilis was 11/100000 and the rate of mother-to-child transmission of hepatitis B was 0.35%,which achieved the goal for eliminating mother-to-child transmission of syphilis and hepatitis B.Conclusion There is still a gap in process indicators and effect indicators of eliminating mother-to-child transmission of AIDS,syphilis and hepatitis B in Guangdong province during 2016 to 2020 compared to the goals of World Health Organization.Intervention indicators were increasing year by year.However,further strengthening of intervention measures is needed to eliminate mother-to-child transmission of AIDS,syphilis and hepatitis B.
作者
高爽
朱颖贤
梁海英
赵莉娜
黄杏枝
夏建红
GAO Shuang;ZHU Ying-xian;LIANG Hai-ying;ZHAO Li-na;HUANG Xing-zhi;XIA Jian-hong(Guangdong Women and Children Hospital,Guangdong 511442,China)
出处
《中国健康教育》
北大核心
2021年第10期872-875,893,共5页
Chinese Journal of Health Education
关键词
消除
母婴传播
艾滋病
梅毒
乙型肝炎
效果
Elimination
Mother to child transmission
AIDS
Syphilis
Hepatitis B
effect
作者简介
高爽(1987-),女,新疆阿勒泰人,大学本科,医师,主要从事消除艾滋病、梅毒和乙肝母婴传播工作;通信作者:夏建红,女,主任医师,研究方向:消除艾滋病、梅毒和乙肝母婴传播。E-mail:xixixia58@126.com。
