摘要
自身抗体对自身免疫病的诊断和鉴别诊断、病情评估、疗效观察、预后判断具有重要意义,因此自身抗体检测准确性至关重要。自身抗体检测技术不断发展,正逐步实现定量化、自动化、智能化,但其检测标准化问题一直没有得到很好解决。本文将对自身抗体检测标准化的现状、发展趋势和如何实现标准化作一述评和讨论。
Based on the fact that autoantibody plays important roles in the regulation of autoimmune disease,it is valuable to improve the accuracy of autoantibody in laboratory to achieve the better diagnosis,classification,disease assessment,effect observation and prognosis analyses of autoimmune diseases.Although the technology of antoantibody measurement is continuously developing and moving towards quantitation,automation and intelligentization in the past years,the standardization of autoimmune testing has still remained challenged.In this paper,the status and trend for autoimmune testing standardization were systematically summarized,and the approaches or strategies to realize standardization were also discussed.
作者
杨再兴
梁艳
Yang Zaixing;Liang Yan(Department of Laboratory Medicine,Huangyan Hospital,Wenzhou Medical University,Taizhou 318020,China;Department of Laboratory Diagnostics,Changzheng Hospital,Naval Medical University,Shanghai 200003,China)
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2021年第11期991-994,共4页
Chinese Journal of Laboratory Medicine
基金
浙江省医药卫生科技项目(2019KY241,2020KY1040)。
关键词
自身抗体
免疫分析
参考标准
Autoantibodies
immunoassay
Reference standards
作者简介
通信作者:杨再兴,Email:yangzaixingdiyi@163.com。
