摘要
目的分析丁苯酞联合依达拉奉对老年脑梗死患者神经功能的影响。方法120例老年急性脑梗死患者,随机分为对照组及观察组,各60例。对照组接受常规化治疗,观察组在对照组基础上应用丁苯酞氯化钠联合依达拉奉治疗。比较两组入院时及治疗1、2周后的临床神经功能缺损评分标准量表(CSS)、美国国立卫生研究院卒中量表(NIHSS)评分及Barthel指数评分。结果治疗1、2周后,观察组CSS、NIHSS评分均低于对照组,差异有统计学意义(P<0.05)。治疗1、2周后,观察组Barthel指数分别为(65.62±7.71)、(85.26±10.25)分,均高于对照组的(46.15±7.28)、(65.26±8.16)分,差异有统计学意义(P<0.05)。结论应用丁苯酞联合依达拉奉治疗老年脑梗死有助于改善患者神经功能缺损,值得进一步在临床推广。
Objective To analyze the effect of butylphthalide combined with edaravone on neurological function in elderly patients with cerebral infarction.Methods A total of 120 elderly patients with acute cerebral infarction were randomly divided into control group and observation group,with 60 cases in each group.The control group was treated with conventional therapy,and the observation group was treated with butylphthalide and sodium chloride and edaravone on the basis of the control group.Both groups were compared in terms of China stroke scale(CSS)score,National Institutes of Health stroke scale(NIHSS)score at and Barthel index at admission and 1,2 weeks after treatment.Results 1 and 2 weeks after treatment,CSS and NIHSS scores of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05).1 and 2 weeks after treatment,the Barthel index of the observation group were(65.62±7.71)and(85.26±10.25)points,which were higher than(46.15±7.28)and(65.26±8.16)points of the control group,and the difference was statistically significant(P<0.05).Conclusion The application of butylphthalide and edaravone is helpful to improve the neurological deficits in elderly patients with cerebral infarction,and it is worthy of further clinical promotion.
作者
徐晓蕊
XU Xiao-rui(Shenyang 245 Hospital,Shenyang 110000,China)
出处
《中国现代药物应用》
2021年第20期93-95,共3页
Chinese Journal of Modern Drug Application
关键词
丁苯酞
依达拉奉
老年脑梗死
神经功能
Butylphthalide
Edaravone
Cerebral infarction in the elderly
Neurological function
