摘要
目的探讨DCE-MRI半定量及定量分析对早期强直性脊柱炎(AS)骶髂关节病变的疗效价值。方法选取并分析48例早期活动性AS。治疗前后均行LAVA-T_(1)WI脂肪抑制动态增强扫描。运用Function tool、GenIQ后处理功能获得ROI的半定量和定量参数值。结果AS治疗后DCE-MRI半定量参数Fenh、Senh和定量参数K^(trans)、K_(ep)、V_(e)较治疗前均降低,TTP较治疗前延长,P<0.05。Fenh、Senh、K^(trans)与BASDAI评分的相关性最高。结论DCE-MRI的半定量和定量分析能够定量评估早期AS骶髂关节骨髓水肿的治疗效果,具有一定的临床价值。
Objective To study quantitative efficacy evaluation of semi-quantitative and quantitative analysis of DCE-MRI in the sacroiliitis of ankylosing spondylitis.Methods Forty-eight patients with early active AS who were 38 males and 10 females.All patients were examined respectively dynamic contrast-enhanced T_(1)WI fat suppression that was performed with LAVA.All indexes of semi quantitative and quantitative of DCE-MRI obtained by using Function tool post-processing and GE MR IQ workstation.Results The indexes of fenh,senh,K^(trans),K_(ep) and V_(e) were lower after treatment than before treatment,while TTP index was longer than before treatment,(all P<0.05).There was the high correlation between the values of Fenh,Senh,K^(trans) and BASDAI score(P>0.05).Conclusion The indexes of semi-quantitative parameters and quantitative parameters of DCE-MRI have can indicate therapeutic response of AS.
作者
李清泰
杨哲
冉荣丽
苏大田
史兆娟
LI Qingtai;YANG Zhe;RAN Rongli;SU Datian;SHI Zhaojuan(Department of Radiology, People's Hospital of Gaotang County, Liaocheng 252000, P.R.China;Department of Radiology, Second Affiliated Hospital of Shandong First Medical University, Taian 271000, P.R.China)
出处
《医学影像学杂志》
2021年第10期1755-1759,共5页
Journal of Medical Imaging
基金
山东省“学术提升计划”项目(编号:2019QL017)
山东省泰安市科技创新发展项目(编号:2020NS122
2020NS246)。
关键词
磁共振成像
半定量、定量分析
强直性脊柱炎
疗效评价
Magnetic resonance imaging
Semi-quantitative and quantitative analysis
Ankylosing spondylitis
Efficacy evaluation
作者简介
李清泰(1984-),男,毕业于泰山医学院,医学硕士,主治医师,主要从事医学影像学诊断工作;通信作者:史兆娟,E-mail:xiaoyunfan2008@126.com。
