摘要
目的探讨个性化延续护理模式干预对2型糖尿病合并冠心病患者焦虑抑郁及血管内皮功能的改善作用。方法选取2019年5月至2020年10月在茂名市人民医院接受治疗的2型糖尿病合并冠心病的60例患者作为研究对象,随机分为处理组和对照组,每组30例,对照组采用常规的护理,处理组则采用个性化延续护理模式,比较两组患者干预前和干预6个月后的焦虑自评量表(SAS)评分和抑郁自评量表(SDS)评分、血清超敏C反应蛋白(h-CRP)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)、一氧化氮(NO)、血管内皮生长因子(VEGF)及内皮素-1(ET-1)的表水平。结果干预6个月后处理组其SAS和SDS评分显著低于对照组(P<0.05),处理组6个月后患者的h-CRP、IL-6显著低于对照组,而IL-10显著高于对照组(P<0.05);处理组6个月后患者的NO、VEGF显著高于对照组,而ET-1显著低于对照组,差异具有统计学意义(P<0.05)。结论基于个性化延续护理模式是一种有效促进2型糖尿病合并冠心病患者缓解焦虑抑郁情绪,改善患者内皮功能的护理方式。
Objective To explore the effect of personalized continuous nursing intervention on anxiety,depression and vascular endothelial function in patients with type 2 diabetes and coronary heart disease.Methods A total of 60 patients with type 2 diabetes and coronary heart disease in Maoming People's Hospital from May 2019 to October 2020 were selected as the research objects.They were randomly divided into a treatment group and a control group,with 30 cases in each group.The control group received routine care,while the treatment group received Adopt personalized continuous care model.The SAS and SDS scores,serum h-CRP,IL-6,IL-10,NO,VEGF and ET-1 levels of the two groups were compared before intervention and after 6 months of intervention.Results After 6 months of intervention,the SAS and SDS scores of the treatment group were significantly lower than those of the control group(P<0.05),and the h-CRP and IL-6 of the treatment group were significantly lower than those of the control group,while IL-10 was significantly higher.Compared with the control group(P<0.05);after 6 months in the treatment group,the NO and VEGF of the patients were significantly higher than the control group,while ET-1 was significantly lower than the control group,the difference was statistically significant(P<0.05).Conclusions Personalized continuation of nursing is a nursing method that effectively promotes the relief of anxiety and depression in patients with type 2 diabetes and coronary heart disease and improves the endothelial function of patients.
作者
黄敏
梁海燕
劳文静
Huang Min;Liang Haiyan;Lao Wenjing(NO.2 Department of Cardiovascular Medicine,Maoming People's Hospital,Maoming 525002,China)
出处
《中华肥胖与代谢病电子杂志》
2021年第3期170-174,共5页
Chinese Journal Of Obesity and Metabolic Diseases:Electronic Edition
关键词
2型糖尿病
个性化
延续护理
冠心病
焦虑抑郁
内皮功能
Type 2 diabetes
Personalized
Continuous care
Coronary heart disease
Anxiety and depression
Endothelial function
作者简介
通信作者:黄敏,Email:940423158@qq.com。