摘要
氮氧自由基是目前最广泛采用的自旋标记物。2,2,6,6-四甲基哌啶氮氧自由基虽然在许多情况下是很稳定的,但是仍然可以发生歧化、单电子氧化还原等反应。其中尤以单电子还原反应会对生物分子的自旋标记产生重大影响。此时氮氧自由基作为一种弱的氧化剂将生物分子中存在的活性集团氧化.
The redox reaction of 2,2,6, 6-tetramethyl-4-hydroxypiperidine-1-oxyl radical with dl-cysteine in buffer solution of different pH has been studied at room temperature under free of oxygen in the dark.It was found that in acidic buffer the oxidation product of cysteine was cysteic acid, in neutral buffer the product was cystine accompanied by a small amount of cysteic acid, whereas in basic buffer the product was cystine only. The reduction product of the nitroxide was identified as the corresponding hydroxylamine in all these cases.
作者
刘有成
汪秀智
刘中立
Liu Youcheng;Wang Xiuzhi;Liu Zhongli(Department of Chemistry,University of Lanzhou,Lanzhou)
出处
《高等学校化学学报》
SCIE
EI
CAS
1983年第2期257-259,共3页
Chemical Journal of Chinese Universities
