摘要
突触可塑性对于维持神经系统的正常活动以及功能十分重要。脑血管疾病已经严重地危害着人类健康,认知障碍是脑卒中后常见并发症之一,针刺治疗脑卒中后认知障碍(PSCI)的作用机制可能与脑的突触可塑性有关。本文从神经保护、突触再生、突触功能等角度总结针刺治疗PSCI的机制,以期为针刺治疗PSCI以及脑卒中后的康复提供临床研究依据。
Synaptic plasticity is important for the maintenance of normal activity of the nervous system and normal neurological function.Cerebrovascular diseases have seriously harmed human health,and cognitive impairment is one of the common complications after stroke.The mechanism of acupuncture in the treatment of post-stroke cognitive impairment(PSCI)may be related to brain synaptic plasticity.This paper summarizes the mechanism acupuncture treatment of PSCI from the perspectives of neuroprotection,synaptic regeneration and synaptic function,so as to provide clinical research basis for acupuncture treatment of PSCI and rehabilitation after stroke.
作者
夏金言
林如辉
XIA Jinyan;LIN Ruhui(Institute of Integrated Traditional Chinese and Western Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;Fujian Key Laboratory of Integrated Traditional Chinese and Western Medicine for Geriatric Diseases,Fuzhou 350122,China)
出处
《广东药科大学学报》
CAS
2021年第5期146-150,共5页
Journal of Guangdong Pharmaceutical University
基金
国家自然科学基金项目(81774386)
福建省自然科学基金项目(2019J01356)。
关键词
脑卒中
认知障碍
突触可塑性
针刺
stroke
cognitive impairment
synaptic plasticity
acupuncture
作者简介
夏金言(1998-),女,在读硕士研究生,从事脑卒中疾病防治研究,Email:1256454647@qq.com;通信作者:林如辉(1980-),男,副研究员,硕士生导师,主要从事脑卒中疾病防治研究,Email:linruhui_2004@sina.com。
