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从“虚、毒、瘀、积”论慢性乙型肝炎及相关肝硬化、肝癌的治疗 被引量:33

Treatment of Chronic Hepatitis B and Related Liver Cirrhosis and Liver Cancer from the Perspective of“Deficiency,Toxin,Stasis and Accumulation”
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摘要 提高中医治疗慢性乙型肝炎及相关肝硬化、肝癌的临床疗效,需要理论创新。结合中医经典理论及慢性乙型肝炎的病理演变过程,认为"虚、毒、瘀、积"是乙型肝炎病毒感染过程中的核心病机,分别采用"补益脾肾、透邪解毒""益气活血化积""养正逐邪、化积解毒"的中医治疗策略。从"虚毒""虚瘀""虚积毒"的动态病机演变来探讨慢性乙型肝炎病毒感染的一体化治疗思路,以期构建慢性乙型肝炎中医病机体系。 Theoretical innovation is urgently needed to improve the clinical effects of traditional Chinese medicine(TCM)in the treatment of chronic hepatitis B(CHB)and related liver cirrhosis and liver cancer.Considering the classical theories of TCM and the pathological evolution of CHB,it is believed that"deficiency,toxin,stasis,and accumulation"are the core pathogenesis in the process of hepatitis B viral infection,and the corresponding TCM treatment strategies are suggested to be"supplementing and boosting spleen and kidney,venting pathogen and resolving toxins","boosting qi,invigorating blood and removing accumulation",and"reinforcing healthy qi,dispelling pathogen,removing accumulation and toxins".From the dynamic pathogenesis of"deficiency-toxin","deficiency-stasis"and"deficiency-accumulation-toxin",the integrated treatment strategy of CHB viral infection has been proposed,so as to construct a TCM pathogenesis system for CHB.
作者 童光东 王宇新 邢宇锋 魏春山 唐海鸿 黄锦桢 黄芙蓉 赖剑萍 陈团团 韩志毅 TONG Guangdong;WANG Yuxin;XING Yufeng;WEI Chunshan;TANG Haihong;HUANG Jinzhen;HUANG Furong;LAI Jianping;CHEN Tuantuan;HAN Zhiyi(The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine,Shenzhen,518033;Shenzhen Traditional Chinese Medicine Hospital,Guangdong Province)
出处 《中医杂志》 CSCD 北大核心 2021年第16期1404-1407,共4页 Journal of Traditional Chinese Medicine
基金 国家自然科学基金(81774263) 2018年艾滋病和病毒性肝炎等重大传染病防治科技重大专项(2018ZX10725505-002) 2020年广东省名中医传承工作室建设项目 深圳市“医疗卫生三名工程”(SZSM201612074)。
关键词 慢性乙型肝炎 乙型肝炎病毒 肝硬化 肝癌 chronic hepatitis B hepatitis B virus cirrhosis liver cancer deficiency stasis toxin accumulation
作者简介 通讯作者:童光东,tgd755@163.com。
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