摘要
目的分析雌孕激素在宫腔镜宫腔粘连分离术后的应用价值。方法选取50例盐城市妇幼保健院在2017年1月至2019年12月间收治的宫腔粘连患进行研究,患者均行宫腔镜宫腔粘连分离术,经抽签法分组,对照组和观察组各25例。对照组用雌激素治疗,观察组用雌孕激素治疗,对比两组总有效率、宫腔粘连程度、子宫内膜厚度、月经量、血流指标和药物不良反应。结果治疗后观察组总有效率、子宫内膜厚度、月经量、子宫内膜穿支血流数高于对照组,宫颈粘连评分、搏动指数和阻力指数低于对照组,差异有统计学意义(P<0.05);治疗后两组药物不良反应比较,差异无统计学意义(P>0.05)。结论在宫腔粘连患者宫腔镜宫腔粘连分离术后运用雌孕激素治疗方案,治疗效果明显,改善月经子宫内膜厚度、血流指标作用明显,药物不良反应无明显提高,临床可应用推广。
Objective To analyze the application value of es trogen and progesterone after hysteroscopic intrauterine adhesions separation.Methods A total of 50 cases of intrauterine adhesions admitted to and treated in Maternal and Child Health Hospital of Yancheng City from January 2017 to December 2019 were researched,and all of them underwent hysteroscopic intrauterine adhesions separation.They were divided into the control group(n=25)and the observation group(n=25)according to the drawing lots grouping method.The control group was treated with estrogen,while the observation group was treated with estrogen and progesterone.The total effective rate,intrauterine adhesion degree,endometrial thickness,menstrual volume,blood flow indices and adverse drug reactions were compared.Results After treatment,the total effective rate,endometrial thickness,menstrual volume and blood flow of endometrial perforator in the obs ervation group were higher than thos e in the control group,while the cervical adhes ion score,pulsatility index and resistance index in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).After treatment,there were no statistically significant differences in adverse drug reactions between the two groups(P>0.05).Conclusion The application of estrogen and progestogen after hysteroscopic separation of intrauterine adhesions in patients with intrauterine adhesions has obvious efficacy.It can improve the thickness of menstrual endometrium and blood flow index obviously,without increasing adverse drug reactions,and can be applied and promoted clinically.
作者
王秀华
WANG Xiuhua(Department of Gynecology,Maternal and Child Health Hospital of Yancheng City,Jiangsu,Yancheng 224000,China)
出处
《中国医药科学》
2021年第14期99-102,共4页
China Medicine And Pharmacy
关键词
雌孕激素
宫腔粘连
子宫内膜厚度
月经量
血流指标
不良反应
Estrogen and progesterone
Intrauterine adhesions
Endometrial thickness
Menstruation volume
Blood flow index
Adverse reaction
