摘要
急性心力衰竭(简称急性心衰)是儿科临床常见的危急重症,但目前儿童急性心衰诊治的循证医学证据较少,针对儿童急性心衰诊治的技术与药物的有效性及安全性的高级别证据匮乏,缺乏治疗理论的创新,且国内外有关儿童急性心衰诊治的共识或指南更新落后,儿童急性心衰临床诊治工作面临巨大的挑战。近年来急性心衰诊治的新技术、新理论在儿童的应用逐步开展,如钙增敏剂及奈西利肽等药物在小儿急性心衰治疗方面逐渐引起重视,血液净化及体外膜肺氧合可明显改善部分急性心衰患儿预后,但未来仍需多中心、大样本、高质量的随机对照研究指导小儿急性心衰的治疗策略。
Acute heart failure(AHF)is a common critical illness in pediatrics.At present,there is a lack of evidence-based diagnosis and drugs for children with AHF.Besides,there is a paucity of reliable evidence on the effectiveness and safety of technologies and drugs for the management of AHF in children.Moreover,the innovation is absent from the treatment theory.Furthermore,the consensus or guidelines on the management of children with AHF are out of date.Therefore,there are huge challenges in the clinical management of children with AHF.In recent years,new drugs and technologies have been applied in the diagnosis and treatment of children with AHF.For example,calcium sensitizers have gradually attracted attention in the treatment of children with AHF,blood purification and extracorporeal membrane oxygenation can significantly improve the prognosis of some children with AHF.Therefore,a multi-center,large sample high-quality and randomized control study is still required to guide the clinical management of children with AHF.
作者
张丽
李伟
Zhang Li;Li Wei(Department of Cardiology,Guangzhou Women and Children′s Medical Center,Guangzhou Medical University,Guangzhou 510120,China)
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2021年第13期975-978,共4页
Chinese Journal of Applied Clinical Pediatrics
关键词
急性心力衰竭
儿童
诊断
治疗
进展
Acute heart failure
Child
Diagnosis
Treatment
Progress
作者简介
通信作者:张丽,Email:zhangliheart2016@163.com。
