摘要
目的探讨不同亚型冠心病患者血清脑钠肽(BNP)水平及临床意义。方法选择2017年7月至2019年12月本院收治的冠心病患者129例,根据不同亚型分为稳定型心绞痛45例(SAP组)、不稳定型心绞痛41例(UAP组)、急性心肌梗死43例(AMI组)。患者均行冠状动脉造影(CAG),对比3组血清BNP、C反应蛋白(CRP)水平及与Gensini积分,并分析血清BNP、CRP与Gensini积分的相关性。结果SAP组、UAP组及AMI组BNP、CRP水平、Gensini积分对比,SAP组最低,UAP组次之,AMI组最高,组间比较差异有统计学意义(P<0.05);经双变量Pearson直线相关检验得出,Gensini积分与BNP、CRP水平呈正相关(P<0.05)。结论不同亚型冠心病BNP、CRP水平、Gensini积分存在显著差异,BNP、CRP水平与Gensini积分呈正相关,有助于早期识别不同亚型冠心病,可作为预后判定指标。
Objective To investigate the serum level of brain natriuretic peptide(BNP)and its clinical significance in patients with different subtypes of coronary heart disease.Methods A total of 129 patients with coronary heart disease admitted to our hospital from July 2017 to December 2019 were selected.According to different subtypes,they were divided into stable angina(SAP group,n=45),unstable angina(UAP group,n=41),and acute myocardial infarction(AMI group,n=43).All patients underwent coronary angiography(CAG).Serum BNP,CRP and Gensini scores were compared among the three groups,and the correlation between BNP,CRP and Gensini scores was analyzed.Results The level of BNP,CRP and Gensini scores in SAP group was the lowest,followed by UAP group and AMI group(P<0.05).According to bivariate Pearson straight-line correlation test,Gensini score was positively correlated with BNP and CRP levels(P<0.05).Conclusion There were significant differences in BNP,CRP level and Gensini scores among different subtypes of coronary heart disease.BNP and CRP levels were positively correlated with Gensini scores,contributing to the early identification of different subtypes of coronary heart disease,and could be used as prognostic indicators.
作者
史洲
SHI Zhou(Department of Clinical Laboratory,Lushan County People′s Hospital,Pingdingshan,Henan 473000,China)
出处
《青岛医药卫生》
2021年第3期199-201,共3页
Qingdao Medical Journal
关键词
冠心病
C反应蛋白
脑钠肽
狭窄
病变
Coronary heart disease
C-reactive protein
Brain natriuretic peptide
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Lesions
