摘要
目的探讨中医药阶段疗法在痰湿型多囊卵巢综合征(PCOS)合并复发性流产中的应用价值。方法将70例痰湿型PCOS合并复发性流产患者按随机数字表法分为试验组和对照组各35例,对照组在予以达英-35,胰岛素抵抗、肥胖者加服二甲双胍,治疗3~6个月至体重质量指数(BMI)、基础性激素正常后予来曲唑促排卵,孕后予地屈孕酮片;试验组在对照组基础上实施中医药阶段疗法,根据体质分型进行中药调理,饮食调养,精神调摄,体育锻炼等治疗,孕后予中药辨证安胎。分别于孕4,8周对2组患者进行血清人绒毛膜促性腺激素(β-HCG)水平检测;于孕12周进行B超检查;对2组患者进行早期先兆流产症候分级量化评估。结果孕4周、8周时,试验组患者β-HCG水平均显著高于对照组(P<0.05);孕12周时,试验组患者治疗有效率、保胎率显著高于对照组(P<0.05);试验组患者早期先兆流产分级量化症候积分显著低于对照组(P<0.05)。结论中医药阶段疗法可显著改善痰湿型PCOS合并复发性流产患者卵巢功能、提高妊娠率与保胎率,是预防PCOS患者反复自然流产的有效措施。
Objective To explore the application value of phase therapy of traditional Chinese medicine in phlegm-damp polycystic ovary syndrome(PCOS)complicated with recurrent miscarriage.Methods Seventy patients with phlegm-damp PCOS complicated with recurrent miscarriage were divided into the experimental group and the control group with 35 cases each according to the random number table.The control group was given Diaing-35,insulin resistance,and obesity plus metformin,and letrozole was given to induce ovulation after 3-6 months of treatment until the body mass index(BMI)and basic sex hormones were normal,and dydrogesterone was given after pregnancy sheet.On the basis of the control group,the experimental group was treated with traditional Chinese medicine phase therapy.According to the physique classification,the treatments such as traditional Chinese medicine conditioning,diet training,mental conditioning,physical exercise,etc.were carried out.After pregnancy,traditional Chinese medicine was used to treat the fetus.The serum levels of human chorionic gonadotropin(β-HCG)were tested at the 4th and 8th weeks of gestation.The B-ultrasound efficacy was checked at the 12th week of gestation.The two groups of patients were assessed for early threatened abortion.Results At the 4th and 8th week of pregnancy,the β-HCG level of the experimental group was significantly higher than that of the control group during the same period(P<0.05).At 12 weeks of gestation,the effective rate of treatment and the fetal preservation rate of the experimental group were significantly higher than those of the control group(P<0.05).The score of early threatened abortion in the experimental group was significantly lower than that in the control group(P<0.05).Conclusion The phase therapy of traditional Chinese medicine can significantly improve the ovarian function of patients with phlegm-dampness PCOS combined with recurrent miscarriage,increase the pregnancy rate and the pregnancy rate,and is an effective strategy to prevent recurrent spontaneous abortion in PCOS patients.
作者
陈清梅
王琼
温静颖
李燕
焦丽敏
Chen Qingmei;Wang Qiong;Wen Jingying(The Nanhai District Sixth People's Hospital of Foshan City,Foshan,Guangdong 528000)
出处
《基层医学论坛》
2021年第13期1886-1888,共3页
The Medical Forum
基金
2019年佛山市自筹经费类科技计划项目(1920001001078)。
关键词
多囊卵巢综合征
复发性流产
痰湿型
中医药阶段疗法
Polycystic ovary syndrome
Recurrent miscarriage
Phlegm-dampness type
Stage therapy of TCM
作者简介
陈清梅,女,硕士,副主任医师。
