摘要
目的探究自体骨与椎间融合器植骨融合治疗腰椎间盘突出并腰椎失稳的临床疗效。方法采用回顾性分析方法,选择2017年1月~2020年1月在本院收治的腰椎间盘突出并腰椎失稳患者74例作为研究对象,根据手术方式的不同分为A组(采用单纯自体骨环形植骨治疗)32例和B组(采用椎间融合器植骨融合治疗)42例。观察两组的手术时间、术中出血量及住院时间,观察两组手术前后的腰椎疾患治疗成绩评分(JOA)及椎间隙高度情况。结果两组的手术时间及术中出血量、住院时间比较,差异无统计学意义(P>0.05)。手术前1天、手术后1个月,两组的JOA评分及椎间隙高度比较,差异无统计学意义(P>0.05)。手术后6个月,两组的JOA评分及椎间隙高度均较手术前1天、手术后1个月高(P<0.05)。手术后1个月,两组的JOA评分及椎间隙高度均较手术前1天高(P<0.05)。手术后6个月,B组的JOA评分及椎间隙高度均较A组高,差异有统计学意义(P<0.05)。结论采用自体骨与椎间融合器植骨融合治疗腰椎间盘突出并腰椎失稳患者,两种治疗方式可明显改善患者的临床症状,提高患者的JOA评分及椎间隙高度。从长期治疗效果来看,椎间融合器植骨融合治疗效果较好。
Objective To investigate the clinical efficacy of the autologous bone graft and interbody fusion cage in lumbar disc protrusion(LDP)complicated with lumbar instability.Methods A total of 74 patients with LDP complicated with lumbar instability admitted to our hospital from January 2017 to January 2020 were selected as the research objects by the retrospective analysis method,and they were divided into group A(n=32,treated with simple autogenous bone ring graft)and group B(n=42,treated with bone graft fusion therapy on intervertebral fusion cage)according to different surgical methods.The operation duration,intraoperative hemorrhage volume and hospitalization time between the two groups were observed,and the score of lumbar disease treatment with Japanese orthopedic association(JOA)and intervertebral space height between the two groups were observed before and after operation.Results There was no statistically significant difference in operation duration,intraoperative hemorrhage volume and hospitalization time between the two groups(P>0.05).There was no statistically significant difference in JOA score and intervertebral space height between the two groups one day before operation and one month after operation(P>0.05).JOA score and intervertebral space height of six months after operation between the two groups were higher than those of one day before operation and one month after operation(P<0.05).JOA score and intervertebral space height of one month after operation between the two groups were higher than those of one day before operation(P<0.05).JOA score and intervertebral space height six months after operation in group B were higher than those in group A,with statistically significant difference(P<0.05).Conclusion Bone graft fusion therapy on autogenous bone and intervertebral fusion cage are used to treat patients with lumbar disc protrusion complicated with lumbar instability.The clinical symptoms,JOA scores and intervertebral space height of the patients are significantly improved by the two treatments.From the aspect of long-term therapeutic efficacy,that of the bone graft fusion therapy on intervertebral fusion cage is better.
作者
王加波
成业东
吴杰
WANG Jiabo;CHENG Yedong;WU Jie(The Second Department of Spinal Surgery,Huaian Medical Treatment Area,General Hospital of Eastern Theater Command of Liberation Army,Jiangsu,Huaian 223000,China)
出处
《中国医药科学》
2020年第24期182-184,244,共4页
China Medicine And Pharmacy
关键词
自体骨
椎间融合器
腰间盘突出
腰椎失稳
Autogenous bone
Intervertebral fusion cage
Lumbar disc protrusion
Lumbar instability
作者简介
通讯作者:成业东。
