摘要
目的探讨基于人乳头瘤病毒(human papilloma viruses, HPV)感染男男性行为人群(men who have sex with men, MSM)性行为模式随时间发展变化趋势,为性行为干预措施提供依据。方法在"MSM乙型肝炎病毒感染对人乳头瘤病毒持续感染的影响"动态队列,对研究对象进行间隔6个月随访,对基线与第一次随访时人口学特征、性行为相关特征进行问卷调查及HPV检测。通过潜在转变分析(latent transition analysis, LTA)对基线性行为模式进行潜在分类并观察其在第1次随访时变化趋势。结果 LTA将MSM人群性行为模式分为性行为低风险、中风险及高风险组3个潜在类别。基线至第1次随访,性行为低风险组保持低风险状态的概率为99.49%,转变为中风险状态的概率为0.51%;性行为中风险组保持为中风险状态的概率为74.88%,转变为低风险状态的概率为22.33%,转变为高风险状态的概率为2.79%,性行为高风险组保持于高风险状态的概率为100.00%。结论 MSM人群性行为模式总体趋于稳定,后期应对高风险人群采取干预措施促进其性行为风险向低风险转变。
Objective To explore the trend of the development of sexual behavior patterns of men who have sex with men(MSM) based on human papilloma viruses(HPV) infection over time, so as to provide evidence for sexual behavior intervention. Methods In dynamic cohort of "effects of hepatitis B virus infection on persistent infection of human papillomavirus in men who have sex with men", the participants were followed up every 6 months, and the demographic characteristics and sexual behaviors of the participants were collected at baseline and the first visit. HPV test was also completed 2 times. The latent transition analysis(LTA) was used to classify the potential states of the sexual behavior patterns at baseline and observe the trend of each potential category over time. Results MSM sexual behavior patterns were divided into three potential categories: sexual behavior low risk group, medium risk group and high risk group by LTA method. Over time, the probability of a low-risk group with a low-risk status at first visit was 99.49%, and the probability of transitioning to a medium-risk state was 0.51%;the probability that the risk group in the sexual behavior remained in the medium-risk state was 74.88%, and the probability of transition to the low-risk state was 22.33%, the probability of transitioning to a high-risk state was 2.79%;and the probability that a high-risk group of sexual behavior remained at high-risk state was 100.00%. Conclusions Sexual behavior patterns of MSM tend to be stable in general, and intervention measures should be taken in high-risk groups in the future period to promote the transition of their sexual behavior risk to low-risk.
作者
陈珍
罗涛
古丽斯亚·海力力
田恬
张国珍
迪力拜尔·阿里木
刘礼荣
戴江红
CHEN Zhen;LUO Tao;GULISIYA Hai-li-li;TIAN Tian;ZHANG Guo-zhen;DILIBAIER A-li-mu;LIU Li-rong;DAI Jiang-hong(Department of Epidemiology and Health Statistics,College of Public Health,Xinjiang Medical University,Urumqi 830011,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2020年第12期1418-1422,共5页
Chinese Journal of Disease Control & Prevention
基金
国家自然科学基金(81560539,81860590)。
关键词
潜在转变分析
男男性行为者
性行为风险
人乳头瘤病毒感染
Latent transition analysis
Sexual risk behavior pattern
Men who have sex with men
HPV infection
作者简介
通讯作者:戴江红,E-mail:epi102@sina.com。
