摘要
目的比较道地与非道地产区白芍药材的质量,以证实文献记载道地产区的合理性。方法收集13个道地及非道地产区共53批白芍药材,HPLC测定没食子酸、儿茶素、芍药内酯苷、芍药苷和苯甲酰芍药苷的含量,并进行主成分分析。结果安徽亳州、浙江杭州、四川中江道地产区的白芍药材质量排名较前,质量好于山西绛县、山东菏泽、河南南阳、河南商丘、广东佛山等非道地产区。结论研究结果证实了白芍道地产区的合理性,为白芍道地性研究奠定了基础。
OBJECTIVE To verify the rationality of Paeoniae Radix Alba from genuine producing areas recorded in literature through comparing the quality of Paeoniae Radix Alba from genuine producing areas and non-genuine producing areas.METHODS The material of Paeoniae Radix Alba of 53 batches were collected from 13 producing areas consist of genuine producing areas and non-genuine producing areas.The content of gallic acid,catechin,albiflorin,paeoniflorin and benzoylpaeoniflorin were simultaneous determined by HPLC,and to make evaluation by principal component analysis.RESULTS Genuine producing areas(Bozhou city of Anhui province,Hangzhou city of Zhejiang province,Zhongjiang county of Sichuan province)ranked the top few in the quality of Paeoniae Radix Alba,which had high quality than non-genuine producing areas(Jiangxian county of Shanxi Province,Heze city of Shandong province,Nanyang city of Henan province,Shangqiu city of Henan province,Foshan city of Guangdong province).CONCLUSION The result has verified partially the rationality of genuine producing areas of Paeoniae Radix Alba,and laid a foundation for further study.
作者
梁伟龙
林钦贤
王斌
王其丰
郭长达
高贯彪
郝建新
LIANG Weilong;LIN Qinxian;WANG Bin;WANG Qifeng;GUO Changda;GAO Guanbiao;HAO Jianxin(Xiangxue Pharmaceutical Co.,Ltd.,Guangzhou 510663,China;Bozhou Huqiao Pharmaceutical Industry Co.,Ltd.,Bozhou 236800,China;Ningxia Longde Liupanshan Traditional Chinese Medicine Resources Development Co.,Ltd.,Guyuan 756300,China)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2020年第24期3000-3004,共5页
Chinese Journal of Modern Applied Pharmacy
基金
中药重点产品行业标准制定计划(ZYY-2017-062)。
关键词
道地产区
白芍
高效液相色谱法
主成分分析
genuine producing area
Paeoniae Radix Alba
HPLC
principal component analysis
作者简介
梁伟龙,男,中药师,Tel:(020)22211977,E-mail:liangwl92@163.com;通信作者:王斌,女,硕士,主管中药师,Tel:(020)22211159,E-mail:wangbin@xphcn.com。
