摘要
硒是生物体不可缺少的微量元素之一,具有重要的生物学功能,但它在功能性和毒性之间的浓度阈值非常窄。纳米硒由于其良好的性能、独特的生物活性以及在营养补充剂和纳米医学应用中的潜力而备受关注。纳米硒作为一种特殊的硒补充剂,具有良好的生物相容性、低毒性、高生物活性等特征。本文简要综述了纳米硒的制备方法,介绍了纳米硒在抗氧化、抗菌、抗癌、药物载体等领域中的生物医学应用研究进展。
Selenium(Se)is considered an essential trace element of fundamental importance for organisms with various biological functions.But it has a very narrow concentration threshold between functionality and toxicity.Selenium nanomaterials have attracted much attention due to their favorable properties,unique biological activities and potential application in nutritional supplements and medical therapy.As a special selenium supplement,selenium-contain nanoparticles(SeNPs)present the characteristics of excellent biocompatibility,low toxicity and high biological activity.This article reviewed the preparation methods of SeNPs,and introduced the application and research progress of SeNPs in the fields of anti-oxidation,anti-bacteria,anti-tumor,anti-cancer drug carrier and biosensors.
作者
苏华华
王艳华
SU Hua-Hua;WANG Yan-Hua(Medical College of China Three Gorges University,Yichang 443002,China)
出处
《生物技术通讯》
CAS
2020年第5期621-626,共6页
Letters in Biotechnology
基金
国家自然科学基金青年项目(81602559)。
关键词
纳米硒
制备
抗菌
抗癌
药物载体
selenium nanomaterials
synthesis
anti-bacteria
anti-tumor
anti-cancer drug carrier
作者简介
苏华华(1990-),女,硕士研究生,(E-mail)398990403@qq.com;通信作者:王艳华,(E-mail)juddy0921@163.com。
