摘要
目的:评价个体化营养干预疗法在妊娠糖尿病(GDM)患者中的应用效果。方法:选择2015年12月~2018年6月期间海南医学院第一附属医院收治的80例GDM住院患者为研究对象,随机将患者分为4组,每组20例。组1采用食物交换份联合血糖指数法;组2采用食物交换份联合血糖负荷法;组3采用血糖指数联合血糖负荷法;组4在食物交换份基础上联合使用血糖指数和血糖负荷法。干预后,观察4组患者的血糖水平、生化指标及胎儿生长发育指标变化。结果:营养干预后,各组患者的血糖水平较干预前均有不同程度下降,差异有统计学意义(P<0.05);为评估4种方法的优劣,进一步对4组患者的血糖水平变化进行组间比较:组1、2、4与组3比较,差异均有统计学意义(P<0.05~0.01),组4与组1、2的晚餐后2 h血糖比较,差异有统计学意义(P<0.05);干预后,4组患者的生化指标及胎儿生长发育指标比较,差异均无统计学意义(P>0.05)。结论:个体化营养干预疗法可使GDM患者血糖水平明显改善,同时满足母体自身生理和胎儿生长发育需求,其中,在食物交换份基础上同时联合血糖指数和血糖负荷的营养干预方式对于患者血糖水平的改善效果更好。
ObjectiveTo evaluate the efficacy of individualized nutritional intervention therapy in patients with gestational diabetes mellitus(GDM).Methods A total of 80 GDM inpatients admitted to the First Affiliated Hospital of Hainan Medical College from December 2015 to June 2018 were selected and divided into 4 groups according to the random number table method,with 20 cases in each group.Food exchange portion combined with glycemic index was used in group 1,food exchange portion combined with blood glucose load in group 2,glycemic index combined with blood glucose load in group 3,and both glycemic index and blood glucose load were used based on food exchange portion in group 4.After intervention,the changes of blood glucose level,biochemical indexes and fetal growth and development indexes of the four groups were determined.Results After nutritional intervention,the blood glucose levels of the patients in four groups were decreased to varying degrees compared with those before the intervention with statistically significant difference(P<0.05).In order to evaluate the advantages and disadvantages of the four methods,the blood glucose levels of the patients in four groups were further compared between groups group 1,2,and 4 showed the significant changes compared with group 3(P<0.01 or 0.05).A significant change in blood glucose level measured 2 h after dinner was observed in group 4 compared with group 1 and 2(P<0.05).In terms of the biochemical indexes and fetal growth and development indexes of the four groups,the differences were not statistically significant(P>0.05).Conclusion Individualized nutritional intervention therapy can significantly improve the blood glucose level of GDM patients,and meet the needs of the mother's own physiology and fetal growth and development.Among all the methods used in this study,the nutrition intervention method that combines the glycemic index and the blood glucose load on the basis of the food exchange portion has a better effect on improving the blood glucose level of the patient.
作者
解丹丹
谢毅强
陈玲玲
李心洁
李晨翠
王晓静
陈小盼
XIE Dan-dan;XIE Yi-qiang;CHEN Ling-ling;LI Xin-jie;LI Chen-cui;WANG Xiao-ing;CHEN Xiao-pan(Department of Clinical Nutrition, the First Affiliated Hospital of Hainan Medical College, Haikou 570102, Hainan, China;College of Traditional Chinese Medicine, Hainan Medical College,Haikou 571199, Hainan, China)
出处
《海南医学院学报》
CAS
2020年第24期1869-1873,共5页
Journal of Hainan Medical University
基金
国家自然科学基金(81860836)
海南医学院第一附属医院科研培育基金(HYFYPY201602)。
关键词
妊娠糖尿病
食物交换份
血糖指数
血糖负荷
营养干预
Gestational diabetes mellitus
Food exchange portion
Glycemic index
Blood glucose load
Nutrition intervention
作者简介
解丹丹(1984-),女,山西人,硕士,主治医师,电话13707572197,E-mailjddfrx99@163.com;通讯作者:陈小盼(1975-),女,海南人,硕士,主任医师,电话13136068962,E-mail 254862958@qq.com。
