摘要
目的:探究血常规、铁代谢检查在不同类型妊娠期贫血孕产妇鉴别诊断中的临床价值。方法:回顾性分析2017年1月~2019年2月在我院就诊的98例妊娠期贫血孕产妇的诊疗情况,根据其贫血类型的不同,又将其分为大细胞贫血(62例)及小细胞贫血组(26例)。选择同时期在我院就诊的45例健康孕产妇作为对照组。分别对其进行血常规及铁代谢检查,分析血常规、铁代谢检查在不同类型妊娠期贫血孕产妇鉴别诊断中的临床价值。结果:小细胞贫血发生的孕周显著的早于大细胞贫血;大细胞贫血主要发生在孕晚期,而小细胞细胞贫血主要发生在孕早中期。两种贫血孕妇Hb明显低于对照组;RBC与对照组无统计学差异;小细胞贫血孕妇MCV、MCH含量明显低于对照组,大细胞贫血孕妇MCV、MCH含量明显高于对照组,且小细胞组妇MCV、MCH含量明显低于大细胞组。大、小细胞贫血孕妇SI、及SF水平显著低于对照组,STfR水平显著高于对照组,且小细胞贫血组SI、及SF水平显著低于大细胞孕妇。两种类型的贫血孕妇血红蛋白浓度(Hb)明显的低于对照组;红细胞的计数(RBC)与对照组无统计学差异;小细胞贫血孕妇红细胞平均体积(MCV)、红细胞平均血红蛋白(MCH)含量明显低于对照组,大细胞贫血孕妇MCV、MCH含量明显的高于对照组,且小细胞组妇MCV、MCH含量明显低于大细胞组。大、小细胞贫血孕妇血清铁(SI)、铁蛋白(SF)水平明显的低于对照组,而其可溶性血清转铁蛋白受体(sTfR)明显的高于对照组,且小细胞贫血组SI、及SF水平显著低于大细胞孕妇。血常规和铁代谢联合检查诊断不同妊娠期贫血的效果显著优于二者单独检查。结论:血常规联合铁代谢检查在不同类型妊娠期贫血孕产妇鉴别诊断中具有较高的临床分析价值,值得在临床广泛推广。
Objective To explore the clinical value of blood routine examination and iron metabolism examination in differential diagnosis of maternal anemia in different types of pregnancy.Methods We retrospectively analyzed the diagnosis and treatment of 98 cases of anemic pregnant women who were diagnosed in our hospital from January 2017 to February 2019.According to the type of anemia,they were divided into large cell anemia(62 cases)and small cells.Anemia group(26 cases).Forty-five healthy pregnant women who were treated in our hospital at the same time were selected as the control group.The blood and iron metabolism were separately examined to analyze the clinical value of blood routine examination and iron metabolism examination in differential diagnosis of maternal anemia during pregnancy.Results Significant gestational weeks earlier than macrocytic anemia occurred in patients with small cell anemia.Large cell anemia occurred mainly in the third trimester,and small cell anemia mainly occurred in the early and middle trimester.Hb in the two anemic pregnant women was significantly lower than that in the control group;there was no significant difference between the RBC and the control group;the MCV and MCH levels in the pregnant women with small cell anemia were significantly lower than those in the control group,and the MCV in the pregnant women with large cell anemia.The content of MCH was significantly higher than that of the control group,and the content of MCV and MCH in the small cell group was significantly lower than that in the large cell group.The SI and SF levels of pregnant women with large and small cell anemia were significantly lower than those of the control group,and the STfR levels were significantly higher than those of the control group.The SI and SF levels of the small cell anemia group were significantly lower than those of the large cell pregnant women.The combined examination of blood routine and iron metabolism to diagnose anaemia in different gestational periods was significantly better than the two groups alone.Conclusion Blood routine combined with iron metabolism examination has high clinical analysis value in differential diagnosis of maternal anemia between different types of pregnancy,and it is worthy of widespread promotion in clinic.
作者
赵晓宁
胡玉芳
Zhao Xiao-ning;Hu Yu-fang(Department of Obstetrics and Gynecology,Beijing Huairou Hospital University of Chinese Academy of Sciences,Beijing 101400,China)
出处
《湖南师范大学学报（医学版）》
2020年第1期53-56,共4页
Journal of Hunan Normal University(Medical Sciences)
关键词
血常规
铁代谢
妊娠期
贫血
blood routine
iron metabolism
pregnancy
anemia
作者简介
通讯作者:胡玉芳,E-mail:253383774@qq.com
