摘要
耐药菌,尤其是多重耐药菌的出现和持续进化给人类健康带来了巨大的威胁。在抗生素逐渐失去特效作用的情况下,科学界和医药界又把眼光重新投向了抗菌的天然生物-噬菌体,并在一些研究中证明了噬菌体可以作为新的武器去替代抗生素治疗耐药菌感染。通过对噬菌体治疗及衍生的裂解酶治疗的世界专利申请进行统计及分析,获得了专利发展趋势、申请人分布特点及主要专利申请人等信息,详细分析了噬菌体及裂解酶治疗的主要专利技术路线和研发热点。
The emergence and continuous evolution of drug-resistant bacteria,especially multi-drug resistant bacteria,poses a huge threat to human health.With the gradual loss of special effects of antibiotics,the scientific community and the medical community have turned their eyes to antibacterial natural organismsbacteriophage,and in some studies have proved that bacteriophage can be used as a new weapon to replace antibiotics to treat drug-resistant bacterial infections.Through statistics and analysis of the world patent applications of phage therapy and derived lyase therapy,information on patent development trends,applicant distribution characteristics and main patent applicants was obtained,and the main patent technology routes and hotspots of bacteriophage and lyase therapy were analyzed in detail.
作者
赵建民
张思源
ZHAO Jian-min;ZHANG Si-yuan(Patent Examination Cooperation Tianjin Center of the Patent Office,CNIPA,Tianjin 300304,China)
出处
《中国生物工程杂志》
CAS
CSCD
北大核心
2020年第10期104-111,共8页
China Biotechnology
关键词
噬菌体
裂解酶
耐药菌
专利技术
Bacteriophage
Lyase
Drug-resistant bacteria
Patent technology
作者简介
通讯作者:赵建民,电子信箱:zhaojianmin_163@126.com;同等贡献:张思源。
