摘要
目的建立气相色谱-质谱法(gas chromatography-mass spectrometry,GC-MS)测定食品接触材料及制品中2,2,4,4-四甲基-1,3-环丁二醇迁移量的分析方法。方法样品采用食品模拟物4%乙酸和95%乙醇浸泡。水基模拟物(4%乙酸)经过乙腈萃取,油脂类模拟物(95%乙醇)旋转蒸干,正己烷定容,用HP-5 MS(30 m×0.25 mm,0.25μm)色谱柱分离后,用气相色谱-质谱法检测,外标法定量。结果本方法检出限0.005 mg/kg;在0.1~2.0 mg/L范围内线性良好,r^2=0.9991;加标浓度为0.1 mg/kg与0.5 mg/kg时,回收率在80.7%~93.7%之间,相对标准偏差(relative standard deviation,RSD)在2.82%~6.22%之间。结论本方法灵敏度高、检测速度快、准确率高,能用于食品接触材料及制品中2,2,4,4-四甲基-1,3-环丁二醇迁移量的测定。
Objective To develop a method for the determination of 2,2,4,4-tetramethyl-1,3-cyclobutanediol migration in food contact materials and products by gas chromatography-mass spectrometry(GC-MS).Methods The samples were soaked in food simulants of 4%acetic acid and 95%ethanol.The water-based simulant(4%acetic acid)was extracted with acetonitrile,the lipid simulants(95%ethanol)was evaporated to dry by rotation,and the volumewas fixed by n-Hexane.The target compounds were separated by HP-5 MS(30 m×0.25 mm,0.25μm)column,detected by GC-MS,and quantitatived by external standard method.Results The limit of detection(LOD)of this method was 0.005 mg/kg.It was showed a good linear relationship between 0.1 mg/L to 2.0 mg/L,r^2 was 0.9991.When the spiked content were 0.1 mg/kg and 0.5 mg/kg,the recoveries were between 80.7%to 93.7%,and the relative standard deviations(RSD)were between 2.82%to 6.22%.Conclusion This method showed high sensitivity,fast detection speed and high accuracy,it can be used to detect the migration amount of 2,2,4,4-tetramethyl-1,3-cyclobutanediol in food contact materials and products.
作者
刘敏芳
周淑美
邢峰
张水锋
谢丽燕
魏旭东
LIU Min-Fang;ZHOU Shu-Mei;XING Feng;ZHANG Shui-Feng;XIE Li-Yan;WEI Xu-Dong(Zhejiang Fangyuan Testing Group Co.,Ltd.,Hangzhou 310018 China)
出处
《食品安全质量检测学报》
CAS
2020年第22期8436-8440,共5页
Journal of Food Safety and Quality
作者简介
通讯作者:刘敏芳,工程师,主要研究方向为食品及相关产品质量安全检测,E-mail:714898786@qq.com。
