摘要
目的探讨胸腔镜肺段切除治疗对早期非小细胞肺癌患者临床疗效及心肺功能的影响。方法将该院在2017年1月—2019年12月收治的40例早期非小细胞肺癌患者根据数字表随机划分为两组,20例设为观察组,另20例作为对照组。对照组患者经过胸腔镜肺叶切除方法治疗,而观察组患者经过胸腔镜肺段切除方法治疗早期非小细胞肺癌。治疗后,对比两组患者的手术情况、手术过程淋巴结清扫的情况,术后并发症发生情况,与此同时,还要对比患者术后的心、肺功能。结果观察组患者手术时间为(91.10±9.34)min显著长于对照组(83.75±9.57)min,差异有统计学意义(t=2.458,P<0.05);术后,观察组每分钟搏出量(SV)和左心射血分数(LVEF)均显著优于对照组,差异有统计学意义(t=5.449、2.130,P<0.05);术后,观察组患者用力呼气肺活量(FVC)数值、1 s用力呼气容量(FEV1)数值以及最大通气量(MVV)数值分别为:(1.78±0.39)L、(1.58±0.14)L、(60.49±10.12)L均显著优于对照组,差异有统计学意义(t=2.064、3.180、2.547,P<0.05)。结论对早期非小细胞肺癌患者实施肺段切除未增加手术风险,能更好的保护心肺功能。
Objective To investigate the effect of thoracoscopic segmentectomy on the clinical efficacy and cardiopulmonary function of patients with early non-small cell lung cancer.Methods The 40 patients with early non-small cell lung cancer admitted to our hospital from January 2017 to December 2019 were randomly divided into two groups according to the number table,20 cases were set as observation group,and the other 20 cases were used as control group.Patients in the control group were treated with thoracoscopic lobectomy,while patients in the observation group were treated with thoracoscopic segmentectomy for early stage non-small cell lung cancer.After treatment,the two groups of patients were compared with the surgical conditions,lymph node dissection during the operation,and postoperative complications.At the same time,the postoperative heart and lung functions of the patients were also compared.Results The operation time of the observation group was(91.10±9.34)min was significantly longer than the control group(83.75±9.57)min,the difference was significant(t=2.458,P<0.05);after the operation,the stroke volume per minute(SV)and left ventricular ejection fraction(LVEF)of the observation group were,which significantly better than the control group,with statistically significant differences(t=5.449,2.130,P<0.05).After the operation,the values of forced expiratory vital capacity(FVC),forced expiratory volume(FEV1)and maximum ventilation(MVV)in the observation group were(1.78±0.39)L,(1.58±0.14)L,(60.49±10.12)L are significantly better than the control group,the difference was statistically significant(t=2.064、3.180、2.547,P<0.05).Conclusion Segmental resection for patients with early stage non-small cell lung cancer does not increase the risk of surgery,and can better protect the cardiopulmonary function,which has a good promotion value.
作者
韩冬
薛东明
陈新于
王峦
朱守营
严文俊
吕作利
HAN Dong;XUE Dong-ming;CHEN Xin-yu;WANG Luan;ZHU Shou-ying;YAN Wen-jun;LYU Zuo-li(Department of Cardiothoracic Surgery,Xuzhou Municipal Hospital,Xuzhou Medical University,Xuzhou,Jiangsu Province,221000 China)
出处
《系统医学》
2020年第22期82-84,共3页
Systems Medicine
关键词
胸腔镜肺段切除
早期非小细胞肺癌
心肺功能
Thoracoscopic segmentectomy
Early non-small cell lung cancer
Cardiopulmonary function
作者简介
韩冬(1975-),男,本科,主任医师,研究方向为胸心外科专业;通信作者:薛东明(1969-),男,本科,副主任医师,研究方向为胸心外科,E-mail:xdm919@sina.com。
