摘要
目的探讨盐酸米诺环素与碘合剂治疗种植体周围炎患者的临床疗效。方法选择我院2018年1~12月收治的292例种植体周围炎患者作为研究对象,按照随机数字表法分为观察组和对照组,每组146例。对照组采用碘合剂治疗,观察组采用盐酸米诺环素治疗,比较两组治疗前、治疗后1、3、6周PLI、PD及SBI值。结果两组治疗后1、3周PLI、PD及SBI均较治疗前下降,且观察组低于对照组,差异有统计学意义(P<0.05)。两组治疗后6周PLI、PD及SBI较治疗后1、3周上升,较治疗前下降,差异有统计学意义(P<0.05);但组间比较,差异无统计学差异(P>0.05)。结论盐酸米诺环素治疗种植体周围炎临床疗效确切,可有效杀灭致病菌,改善患者PLI、PD、SBI指标,但药物时效性在治疗6周后下降,应每隔3周进行重复治疗,以有效保持药物浓度。
Objective This study aims to explore the clinical effect of minocycline hydrochloride and iodine mixture in the treatment of peri-implant inflammation.Methods 292 patients admitted to our hospital from January 2018 to December 2018 were randomly divided into observation group(n=146)and control group(n=146).The control group was treated with iodine mixture and the observation group with minocycline hydrochloride.The PLI,PD and SBI values of the two groups before treatment,1,3,and 6 weeks after treatment were compared.Results The PLI,PD and SBI of the two groups were lower than before the treatment at 1,3 weeks after treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The PLI,PD and SBI of the two groups increased at 6 weeks after treatment compared with 1,3 weeks after treatment,and decreased compared with before treatment,the difference was statistically significant(P<0.05);but there was no statistical difference between the groups(P>0.05).Conclusion Minocycline hydrochloride has a definite clinical effect in the treatment of peri-implantitis.It can effectively kill pathogenic bacteria and improve patients'PLI,PD,and SBI indicators.However,the time-effectiveness of the drug decreases after 6 weeks of treatment,and the treatment should be repeated every 3 weeks.To effectively maintain drug concentration.
作者
郝亚柯
李学智
HAO Ya-ke;LI Xue-zhi(Department of Oral Medicine,General Hospital of Xining First Medical Group,Xining 810000,Qinghai,China)
出处
《医学信息》
2020年第23期144-146,共3页
Journal of Medical Information
关键词
盐酸米诺环素
碘合剂
种植体周围炎
龈沟出血指数
探诊深度
Minocycline hydrochloride
Iodine mixture
Peri-implantinflammation
Gingival crevicular bleeding index
Probing depth
作者简介
郝亚柯(1986.4-),女,内蒙古鄂尔多斯人,本科,主治医师,主要从事牙体牙髓及牙周病诊治工作。
