摘要
目的比较甲亢应用抗甲状腺药物、131I治疗的效果。方法抽取我院2018年3月至2019年6月收治的甲亢患者73例为研究对象,35例行抗甲状腺药物治疗者作为对照组,38例行131I治疗者作为实验组,观察两组甲状腺功能及骨代谢变化情况,并对远期治疗效果进行评估。结果①实验组治疗后甲状腺功能指标(TT4、FT4、TSH)水平显著优于对照组(P<0.05);②实验组治疗后骨代谢指标(BGP、PINP、ALP)水平显著低于对照组(P<0.05);③随访6个月,实验组复发率及甲减发生率显著低于对照组(P<0.05)。结论甲亢治疗中抗甲状腺药物、131I均能发挥一定疗效,后者近远期效果更佳,故建议选择131I。
Objective To compare the therapeutic effect of antithyroid drugs and 131I on hyperthyroidism.Methods 73 patients with hyperthyroidism admitted to our hospital from March 2018 to June 2019 were selected as the study objects,35 patients with antithyroid drugs as the control group,38 patients with 131I as the experimental group,to observe the changes of thyroid function and bone metabolism in the two groups,and to evaluate the long-term treatment effect.Results①The level of thyroid function index(TT4,FT4,TSH)in the experimental group was significantly higher than that in the control group(P<0.05).②The level of bone metabolism index(BGP,PINP,ALP)in the experimental group was significantly lower than that in the control group(P<0.05).③After 6 months of follow-up,the recurrence rate and hypothyroidism rate in the experimental group were significantly lower than that in the control group(P<0.05).Conclusion In the treatment of hyperthyroidism,both antithyroid drugs and 131I can play a certain effect,the latter has better short-term and long-term effect,so it is suggested to choose 131I.
作者
孙文强
沈丹丹
SUN Wen-qiang;SHEN Dan-dan(Department of endocrinology,The People's Hospital of Pingyi County,Linyi,Shandong 273300)
出处
《智慧健康》
2020年第22期132-133,140,共3页
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