摘要
目的:观察自拟方剂补肾活血方治疗多发性大动脉炎临床疗效。方法:选取2018年10月—2019年10月于本院周围血管病科住院治疗的多发性大动脉炎患者68例,将68例多发性大动脉炎患者随机分为观察组与对照组各34例,两组均给予静点丹参川芎嗪注射液、银杏叶提取物注射液基础治疗,观察组加用自拟方剂补肾活血方1剂/日,分2次口服,两组均治疗4周,观察治疗前后血沉、血清C反应蛋白(CRP)、临床症状和体征,双足皮温变化情况,评估临床疗效。结果:观察组治疗后血沉、CRP水平降低程度高于对照组(P<0.05),临床症状和体征均较入院前有所改善,观察组有效率高于对照组,观察组治疗效果明显优于对照组(P<0.05)。治疗前后红外热像检查双足皮温,两组治疗皮温均明显改善,观察组皮温升高较对照组明显(P<0.05)。结论:自拟方剂补肾活血方在临床上对多发性大动脉炎具有良好的疗效。
Objective:To observe the clinical efficacy of Bushen Huoxue Formula in the treatment of Takayasu arteritis.Methods:68 patients with Takayasu arteritis were randomly divided into the observation group(n=34)and the control group(n=34).The control group was treated with Danshen Chuanxiongqin Injection and Ginkgo Biloba Extract(GBE)Injection;on which basis,the observation group was also treated with self-made Bushen Huoxue Formula.The treatment duration was 4 weeks.The erythrocyte sedimentation rate,serum C-reactive protein(CRP),clinical symptoms and signs,and changes in skin temperature of the feet were observed before and after the treatment in the two groups,and the clinical efficacy was evaluated.Results:The levels of erythrocyte sedimentation rate and CRP in the observation group were lower than those in the control group after the treatment(P<0.05).The clinical symptoms and signs were improved after the treatment in the two groups.The effective rate of the observation group was higher than that of the control group.The therapeutic effect of the observation group was significantly better than that of the control group(P<0.05).Before and after the treatment,the infrared thermography was used to check the skin temperature of both feet.The skin temperature was significantly improved in the two groups after the treatment;the skin temperature in the observation group was significantly higher than that in the control group(P<0.05).Conclusion:Self-made Bushen Huoxue Formula has a good curative effect on Takayasu arteritis in clinic.The treatment in the observation group is safe and effective,which is superior to that in the control group.
作者
安喆
杨超
陈文阁
AN Zhe;YANG Chao;CHEN Wenge(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《中医药学报》
CAS
2020年第11期46-49,共4页
Acta Chinese Medicine and Pharmacology
基金
黑龙江省自然科学基金项目(H201475)。
关键词
多发性大动脉炎
补肾活血方
血沉
皮温
Takayasu arteritis
Bushen Huoxue Formula
ESR
Skin temperature
作者简介
安喆(1994-),男,硕士研究生,研究方向:中西医结合治疗周围血管病;通讯作者:陈文阁(1967-),男,主任医师,教授,硕士生导师,研究方向:中西医结合治疗周围血管病。
