摘要
目的:观察清热解毒中药内服联合外熏对肛周脓肿及肛瘘术后创面的影响。方法:将100例肛周脓肿及肛瘘患者为对象,均行手术治疗,按电脑数字表法随机分为2组,每组各50例,对照组术后施予高锰酸钾溶液熏洗,试验组施予清热解毒中药内服联合外熏治疗,对比2组创面愈合质量、炎症因子、渗液评分及疼痛评分变化。结果:术后当天,2组血清肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)及白细胞介素-8(IL-8)水平比较,差异无统计学意义(P>0.05)。治疗后,2组血清TNF-α、IL-1β及IL-8水平均降低,且试验组比对照组更低,差异有统计学意义(P<0.05)。治疗后,试验组创面愈合时间、腐肉脱落时间均比对照组短,而试验组创面愈合度比对照组高,同时试验组肉芽生长评分比对照组低,差异有统计学意义(P<0.05)。术后当天,2组渗液评分及疼痛评分比较,差异无统计学意义(P>0.05)。治疗后,2组渗液评分及疼痛评分均降低,且试验组比对照组更低,差异有统计学意义(P<0.05)。结论:清热解毒中药内服联合外熏有助于促进肛周脓肿及肛瘘术后患者创面愈合,并提升创面愈合质量。
Objective: To observe the effect of Qingre Jiedu therapy through oral administration of Chinese medicine combined with external fumigation on perianal abscess and wounds after surgery of anal fistula. Methods: A total of 100 cases of patients with perianal abscess and anal fistula were selected as the objects and randomly divided into two groups according to the computer number table method, 50 cases in each group. Both groups were treated with surgery. After surgery,the control group was given fumigation with potassium permanganate solution;the experiment group was given Qingre Jiedu therapy through oral administration of Chinese medicine combined with external fumigation. The quality of wound healing and the changes in scores of inflammatory factors, exudate and pain were compared between the two groups. Results:On the day after operation,when compared the levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β) and interleukin-8(IL-8) in serum between the two groups, there was no significance in the difference(P>0.05). After treatment,the levels of TNF-α,IL-1β and IL-8 in serum in the two groups were decreased,and the three levels in the experiment group were lower than those in the control group,the difference being significant(P<0.05). After treatment,the time of wound healing and slough shedding in the experiment group were shorter than that in the control group;the degree of wound healing in the experiment group was higher than that in the control group;the score of granulation growth in the experiment group was lower than that in the control group, the difference being significant(P<0.05). On the day after operation, when compared the scores of exudate and pain between the two groups, there was no significance in the difference(P>0.05). After treatment,the scores of exudate and pain in the two groups were decreased;the two scores in the experiment group were lower than those in the control group,the difference being significant(P<0.05). Conclusion:The therapy of Qingre Jiedu therapy through oral administration of Chinese medicine combined with external fumigation conduces to promoting wound healing after surgery of anal fistula in patients with perianal abscess,and improving the quality of wound healing.
出处
《新中医》
CAS
2020年第18期85-88,共4页
New Chinese Medicine
基金
2017年柯桥区社发类经费自筹科技计划项目(2017KZ079)。
关键词
肛周脓肿
肛瘘
清热解毒法
外熏
创面愈合
内外合治
Perianal abscess
Anal fistula
Qingre Jiedu therapy
External fumigation
Wound healing
Combined internal and external treatment
作者简介
叶国勇(1983-),男,主治医师,研究方向:全科。
