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新型冠状病毒肺炎的临床特征及计算机断层成像的影像学特征 被引量:2

Clinical and computed tomography imaging features of corona virus disease 2019
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摘要 目的通过分析新型冠状病毒肺炎(COVID-19)患者的临床特征和胸部计算机断层成像(computed tomography,CT)表现,为早期诊断和临床治疗提供影像学依据。方法纳入2020年1月23日至2月22日于瑞安市人民医院就诊且咽拭子2019新型冠状病毒核酸检测为阳性的74例COVID-19患者,分析其临床资料及CT检查图像特点。结果74例患者中,62例(83.8%)发热;59例胸部CT检查存在异常表现,15例CT检查无异常改变。从起病到CT检查的平均间隔时间为4.6 d。59例患者中,58例(98.3%)病变分布以外周为主,病变多发53例(91.4%),单发结节灶5例(8.6%);45例(76.3%)患者以磨玻璃影表现为主;病灶主要分布于肺部中下叶,共45例(76.3%);支气管充气征21例(35.6%),反晕征10例(16.9%);其他少见改变有小空泡征3例(5.1%),树芽征1例(1.7%),复查发现淋巴结增大2例(3.4%)。结论COVID-19患者的CT检查特征可在其早期诊断和随访中发挥重要作用。 Objective To analyze the clinical features and imaging findings of chest computed tomography(CT)of patients with corona virus disease 2019(COVID-19),and to provide imaging guidance for early diagnosis and clinical treatment.Methods A total of 74 patients diagnosed with positive nucleic acid test of nasopharyngeal swab were retrospectively collected from January 23 to February 22,2020 in the inpatient department of Rui′an People′s Hospital.Their clinical features were analyzed in combination with CT image characteristics.Results Of the 74 patients,62(83.8%)had fever,59 had abnormalities in CT examinations and 15 patients had no imaging abnormalities.The average interval from onset to CT examination was 4.6 days.Among 59 patients,58 cases(98.3%)were mainly peripherally distributed,53 cases(91.4%)had multiple lesions and five cases(8.6%)had single nodules.The main manifestation was ground glass opacities(45 cases,76.3%).The lesions were mainly distributed in the middle and lower lobe of the lungs,accounting for 76.3%(45 cases).Air bronchogram was shown in 21 cases(35.6%),and reversed halo sign was shown in 10 cases(16.9%).Other rare abnormalities were small cavities in three cases(5.1%),tree-in-bud pattern in one case(1.7%).Intrathoracic lymph node enlargement was found in two cases(3.4%)by re-examination.Conclusion The CT examination characteristics of COVID-19 patients could play an important role for early diagnosis and follow-up.
作者 王晓阳 刘晨彬 施德恩 袁翠云 孙庆丰 Wang Xiaoyang;Liu Chenbin;Shi De′en;Yuan Cuiyun;Sun Qingfeng(Department of Radiology,Rui′an People′s Hospital,Wenzhou 325200,Zhejiang Province,China;Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Shenzhen 518116,China;Department of Infectious Diseases,Rui′an People′s Hospital,Wenzhou 325200,Zhejiang Province,China)
出处 《中华传染病杂志》 CAS CSCD 2020年第10期631-634,共4页 Chinese Journal of Infectious Diseases
基金 瑞安市科学技术局基金(MS2020023、MS2020025)。
关键词 冠状病毒感染 肺炎 2019新型冠状病毒 临床特点 体层摄影术 螺旋计算机 Coronavirus infections Pneumonia 2019 novel coronavirus Clinical features Tomography,spiral computed
作者简介 对本文有同等贡献:王晓阳;对本文有同等贡献:刘晨彬;通信作者:孙庆丰,Email:sunxue0806@126.com,电话:13511486270。
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