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微创拔牙术对下颌阻生智齿患者TNF-α、IL-6的影响

Application Effect of Minimally Invasive Tooth Extraction in the Extraction of Impacted Wisdom Teeth
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摘要 目的研究微创拔牙术对下颌阻生智齿患者肿瘤坏死因子-α(TNF-α)白细胞介素-6(IL-6)的影响。方法选取2018年9月至2019年9月莱芜钢铁集团有限公司医院收治的下颌阻生智齿患者116例进行研究,按照随机数字表法分为对照组和试验组,每组58例。对照组使用传统拔除术,试验组则使用微创拔牙术。比较两组手术情况,手术前后血清TNF-α、IL-6水平的变化以及术后并发症发生率。结果试验组的术中出血量,手术时间,视觉模拟(VAS)评分均低于对照组(P<0.05);与术前相比,术后5 d两组血清TNF-α、IL-6水平均升高,但试验组术后5 d血清TNF-α、IL-6水平低于对照组;试验组的术后并发症发生率为12.07%,低于对照组的27.59%,差异有统计学意义(P<0.05)。结论下颌阻生智齿患者使用微创拔牙术效果显著,可减少术中出血量,缩短手术时间,减轻疼痛程度,抑制炎症反应,降低术后并发症发生率。 Objective To investigate the effect of minimally invasive tooth extraction on TNF-α and IL-6 in patients with impacted wi sdom teeth.Methods A total of 116 patients with impacted mandibular wisdom teeth in Laiwu Iron and Steel Group Co.,Ltd.Hospital from September 2018 to September 2019 were divided into control group and exper imental group according to different operation methods,58 case8 in each group.Traditional extraction was used in the control group and minimally invasive extraction was used in the experinental group.The changes of serum TNF-α and IL-6 levels before and after operation and the incidence of postoperative comp1 ications were compared between the two gtoups.Results The bleeding volume,operation time and VAS score of the experimental group were lower than those of the control group(P<0.05).Compared with that before operation,the levels of TNF-α and IL-6 in the serum of the experimental group were lower than that of the control group on the 5th day after operation,and the incidence of postoperative complications in the experimental group was 12.07%,lower than that of the control group(27.59%,P<0.05).Conclusion Minimally invasive tooth extraction surgery has a si gni ficant effect on patients with impacted mandi bular wi sdom teeth,which can reduce intraoperative blood loss,shorten the operation time,reduce the degree of pain,inhibit inf lamnatory response,and reduce the incidence of pos toperative compl ications,worth promotion and application.
作者 刘丰宝 许文文 LIU Fengbao;XU Wenwen(Laiwu Iron and Steel Group Co.,Ltd.Hospital,Laiwu,Shandong 271104,China)
出处 《大医生》 2020年第6期39-39,40,41,共3页 Doctor
关键词 微创拔牙术 下颌阻生智齿 肿瘤坏死因子-Α 白细胞介素-6 minimally invasive tooth extraction impacted mandibular wisdom teeth tumor necrosis factor-α inter leukin-6
作者简介 刘丰宝,本科,主治医师,研究方向:口腔外科。
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