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病毒性脑炎后遗症期继发性癫痫影响因素分析 被引量:2

Influencing Factors of Secondary Epilepsy in Sequelae Stage of Viral Encephalitis
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摘要 目的:分析病毒性脑炎(VE)后遗症期继发性癫痫的影响因素。方法:选取本院2016年12月-2019年12月收治的65例VE患者,将后遗症期出现继发性癫痫的患者作为试验组,未发生继发性癫痫的患者作为参照组,分析VE患者后遗症期发生继发性癫痫的影响因素。结果:65例VE患者中,20例(30.77%)出现继发性癫痫,45例(69.23%)未出现继发性癫痫。两组昏迷人数、昏迷持续时间、急性期癫痫发作次数、脑电图异常程度及颅脑MRI信号异常情况比较,差异均有统计学意义(P<0.05)。昏迷、昏迷持续时间、急性期癫痫发作次数、脑电图异常程度及颅脑MRI信号异常为VE后遗症期继发性癫痫的危险因素,差异均有统计学意义(P<0.05)。结论:昏迷、昏迷持续时间、急性期癫痫发作次数、脑电图异常程度及颅脑MRI信号异常均为VE后遗症期继发性癫痫的危险因素,临床中应对高危人群引起重视,给予针对性处理。 Objective:To analyze the influencing factors of secondary epilepsy in the sequelae stage of viral encephalitis(VE).Method:A total of 65 patients with VE admitted to our hospital from December 2016 to December 2019 were selected.Patients with secondary epilepsy in sequelae stage were taken as the experimental group and those without secondary epilepsy as the reference group.The influencing factors of secondary epilepsy in sequelae stage of VE patients was analyzed.Result:Among 65 VE patients,20 cases(30.77%)had secondary epilepsy,and 45 cases(69.23%)had no secondary epilepsy.There were statistically significant differences in coma,duration of coma,number of seizures in acute phase,abnormal degree of EEG and abnormal brain MRI signal between the two groups(P<0.05).Coma,duration of coma,number of seizures in the acute phase,abnormal degree of EEG and abnormal brain MRI signal were risk factors for secondary epilepsy in the sequelae stage of VE(P<0.05).Conclusion:Coma,duration of coma,number of epileptic seizures in the acute phase,abnormal degree of EEG and abnormal brain MRI signal are risk factors for secondary epilepsy in the sequelae stage of VE.The high-risk population should be paid more attention in clinic,and targeted treatment should be given.
作者 黄运强 何锦照 马国重 钟广宏 HUANG Yunqiang;HE Jinzhao;MA Guozhong;ZHONG Guanghong(Heyuan People’s Hospital,Heyuan 517000,China;不详)
出处 《中国医学创新》 CAS 2020年第21期112-115,共4页 Medical Innovation of China
关键词 病毒性脑炎 后遗症期 继发性癫痫 Viral encephalitis Sequelae stage Secondary epilepsy
作者简介 通信作者:黄运强。
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