摘要
目的利用气相色谱串联质谱联用仪(GC-MS/MS)建立食品包装纸中24种有害物质(17种邻苯二甲酸酯(PAEs)和7种多氯联苯(PCBs))同时测定的方法。方法样品处理后准确加入30 mL异丙醇和内标溶液,超声萃取40min,使用气相色谱串联质谱仪进行检测,并采用内标法定量。结果在0.02~1.0μg/mL范围内,24种化合物的拟合曲线线性良好,相关系数R^2在0.9945~1.0000之间,方法检出限和定量限分别为0.0005~0.0028 mg/L和0.0016~0.0089 mg/L,6种不同品牌的食品包装纸种的最高残留量为26.53 mg/kg。对24种化合物进行低、中、高3个水平浓度的加标回收试验,发现平均回收率在85.6%~109.7%之间,日内和日间的相对标准偏差分别小于6%(n=5)和9%(n=3),回收率、重复性及精密度良好。结论该方法简便、快速、结果准确可靠,适用于同时测定食品包装纸中24种有害物质,是一种高通量测试方法。
The work aims to establish a method for the simultaneous determination of 24 harmful substances(17 PAEs and 7 PCBs) and 7 polychlorobiphenyl(PCBs) in food packaging paper by GC-MS/MS. After sample treatment, 30 mL isopropanol and internal standard solution were added accurately and gas chromatography tandem mass spectrometry was used for detection after ultrasonic extraction for 40 min. Then, the internal standard method was adopted for quantification. In the range of 0.02-1.0 mg/L, the linearity of fitting curves of the 24 compounds was good and the correlation coefficient was in the range of 0.9945-1.0000. The limit of detection and the limit of quantitation were 0.0005-0.0028 and 0.0016-0.0089 μg/mL, respectively. The highest content in 6 kinds of food packaging paper was 26.53 mg/kg. The recovery experiments were carried out to 24 compounds at low, medium and high levels and the average recovery rate was from 85.6% to 109.7%. The relative standard deviations within and between days were less than 6%(n=5) and 9%(n=3), respectively and the recovery rate, repeatability and accuracy were good. This method is simple, rapid, accurate and reliable. It is high-throughput and suitable for the simultaneous determination of 24 kinds of harmful substances in food packaging paper.
作者
张霞
崔卓
谢丽华
王文婷
臧志鹏
王洪波
翟玉俊
ZHANG Xia;CUI Zhuo;XIE Li-hua;WANG Wen-ting;ZANG Zhi-peng;WANG Hong-bo;ZHAI Yu-jun(Technology Center,GANSU Tobacco Industrial Co.,Ltd.,Lanzhou 730050,China;Zhengzhou Tobacco Research Institute of CNTC,Zhengzhou 450001,China)
出处
《包装工程》
CAS
北大核心
2020年第17期152-159,共8页
Packaging Engineering
作者简介
张霞(1982-),女,硕士,工程师,主要研究方向为烟草原料和烟用辅料的检测;通信作者:王洪波(1975-),男,研究员,主要研究方向为烟草化学。
