摘要
目的探究并分析系统急救干预结合预警理念的质量控制对连续性血液净化(continuous blood purifica⁃tion,CBP)治疗的顽固性心力衰竭(intractable heart failure,RHF)患者心功能、生活质量及预后的影响。方法选取2016年1月—2019年9月铜陵市立医院院收治的60例患者需经行CBP治疗的RHF患者,按照随机数字表将其分为观察组及对照组,每组30例。对照组患者给予系统急救干预,观察组患者在对照组的基础上给予预警理念的质量控制。观察并记录两组患者干预前后EF值、生存质量评分、预后情况、生存曲线。结果两组患者年龄、性别、体重、顽固性心力衰竭病因、NYHA分级等比较无明显差异(P>0.05);干预前两组患者EF值均无明显差异(P>0.05),干预后两组EF值明显增加(P<0.05),观察组患者EF值明显优于对照组患者(P<0.05);经重复方差分析,两组患者干预前后生存质量评分比较差异明显(F=11.13,P=0.002),治疗前两组患者生存质量无显著差异(P>0.05),干预后两组患者生存质量评分均显著升高(P<0.05);两组患者再住院次数、首次间隔天数比较差异明显(P<0.05),观察组再住院次数显著低于对照组(P<0.05),首次间隔天数显著高于对照组(P<0.05);两组患者生存曲线可见观察组生存时间显著长于对照组(P<0.05),具有统计学意义。结论系统急救干预联合预警理念的质量控制能有效改善行CBP治疗的RHF患者心功能及生存质量,增加患者生存时间,值得临床推广。
Objective To explore the influence of quality control of systematic first aid intervention combined with early warning concept on the cardiac function,quality of life,and prognosis of patient with refractory heart failure(RHF)treated with continuous blood purification(CBP).Methods 60 RHF patients were randomly divided into 2 demographical and clinical data-matched groups:control group undergoing CBP for 3 months and observation group given quality control of systematic first aid intervention combined with early warning concept in addition.The ejection fraction(EF)values before and 3 months after treatment,and the life quality scores,numbers of re-hospitalization and interval days between the first and second admissions 3 months after treatment were recorded.The Kaplan-Meier survival curves were drawn.Results There were no significant differences in the EF values between the two groups before and after the intervention(bothP>0.05),and the EF value of the observation group was significantly higher than that of the control group 3 months after treatment(P<0.05).Repeated analysis of variance showed that the life quality scores 1,3,and 6 months after treatment of the observation group were all significantly higher than those of the control group(F=11.13,P=0.002,f=8.21,P=0.024,f=9.47,P=0.013)..The number of re-hospitalization of the observation was significantly lower than that of the control group.The interval days between the first and second admission of the observation group was(25.84±8.2)days,significantly less than that of the control group[(18.32±8.3)days,P=0.011].The survival curve showed that the patients of the observation group survived significantly longer than those of the control group(P<0.05).Conclusion The quality control of systematic first aid intervention combined with early warning concept effectively improves the heart function and quality of life of RHF patients treated with CBP,and increases the survival time of patients.
作者
徐琴
刘丽
王欢
方明燕
余琴琴
XU Qin;LIU Li;WANG Huan;FANG Mingyan;YU Qinqin(Department of Critical Care Medicine,Tongling Municipal Hospital,,Tongling 244000,China)
出处
《中国急救复苏与灾害医学杂志》
2020年第8期944-947,共4页
China Journal of Emergency Resuscitation and Disaster Medicine
基金
铜陵市科技计划项目(编号:2017NS04)
安徽省高校自然科学基金重点项目(编号:KJ2017A264)。
关键词
顽固性心力衰竭
心功能
生存质量
预后
Refractory heart failure(EHF)
Cardiac function
Quality of life
Prognosis
Continuous blood purification(CBP)
作者简介
通信作者:刘丽,E-mail:249845076@qq.com。
