摘要
目的:观察靶控输注(TCI)右美托咪定对妇科腹腔镜手术患者麻醉恢复期的影响。方法:选择2018年1月-2019年12月于笔者所在医院择期拟行妇科腹腔镜次全子宫切除术患者40例,按随机数字表法将其分为R组(20例)、D组(20例)。手术结束前40 min,D组TCI右美托咪定,R组输注等量生理盐水。比较两组血流动力学指标[心率(HR)、收缩压(SBP)、舒张压(DBP)]、拔管时间及Steward苏醒评分。结果:T1时两组HR、SBP、DBP对比差异无统计学意义(P>0.05);T2、T3、T4时D组SBP[(107.37±6.80)、(114.72±5.94)、(110.87±6.19)mm Hg]、DBP[(66.41±4.53)、(69.82±5.37)、(74.24±6.29)mm Hg]均低于R组,T2、T3时D组HR[(76.17±12.30)、(84.34±10.86)次/min]均低于R组,差异均有统计学意义(P<0.05);D组拔管时间早于R组,Steward苏醒评分高于R组,差异均有统计学意义(P<0.05)。结论:TCI右美托咪定用于妇科腹腔镜手术,患者血流动力学更稳定,能够提高麻醉苏醒质量,缩短拔管时间,可作为妇科腹腔镜手术中较为理想的麻醉方案。
Objective:To observe the effect of target controlled infusion (TCI) of Dexmedetomidine on the anesthesia recovery period of patients undergoing gynecological laparoscopic surgery.Method:Forty patients scheduled for gynecological laparoscopic subtotal hysterectomy in our hospital from January 2018 to December 2019 were selected,and were randomly divided into group R (n=20) and group D (n=20).Forty minutes before the end of the operation,TCI of Dexmedetomidine was given in group D,and the same amount of normal saline was infused in group R.The hemodynamic parameters [heart rate (HR),systolic blood pressure (SBP),diastolic blood pressure (DBP)],extubation time and Steward awakening score were compared between the two groups.Result:There was no significant difference in HR,SBP and DBP between the two groups at T1(P>0.05).At T2,T3,T4,the SBP [(107.37±6.80),(114.72±5.94),(110.87±6.19) mm Hg],the DBP [(66.41±4.53),(69.82±5.37),(74.24±6.29) mm Hg] in group D were lower than those in group R,at T2,T3,the HR [(76.17±12.30),(84.34±10.86) times/min] in group D were lower than those in group R,the differences were statistically significant (P<0.05).The extubation time in group D was earlier than that in group R,and the Steward awakening score in group D was higher than that in group R,the differences were statistically significant (P<0.05).Conclusion:TCI of Dexmedetomidine in gynecological laparoscopic surgery is more stable in hemodynamics,can improve the quality of anesthetic recovery and shorten the extubation time,so it can be used as an ideal anesthetic scheme in gynecological laparoscopic surgery.
作者
刘羽
刘滨
方敏
谭成杰
包胜华
LIU Yu;LIU Bin;FANG Min;TAN Chengjie;BAO Shenghua(Dongguan Sanju Hospital,Dongguan 523710,China;不详)
出处
《中外医学研究》
2020年第17期38-40,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
广东省东莞市科技计划医疗卫生类科研项目(2018507150681132)。
关键词
妇科腹腔镜手术
右美托咪定
靶控输注
血流动力学
Gynecological laparoscopic surgery
Dexmedetomidine
Target controlled infusion
Hemodynamics