摘要
目的探讨分级检验方法和常规拉网式检验法两种不同检验方法对血脂相关指标的影响。方法将2018年5~6月荔联社区中血脂检测的360例老年人(年龄60~80岁,其中男198例,女162例)随机分为分级检验组[n=180,男97例,女83例,平均年龄(73.5±0.3)岁]和常规拉网式检验组[n=180,男101例,女79例,平均年龄(72.7±0.4)岁],两组被检测人员在性别以及年龄方面比较,差异无统计学意义(P>0.05)。两组检测人员分别予以分级检验方法及常规拉网式检验方法检测血液中的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)六个指标,分析两种检验方法的检验结果、阳性检出率以及漏检率等数据,对比两种不同检验方法对血脂相关指标的影响。结果分级检验法TC、TG、HDL-C、LDL-C、ApoAI、ApoB分级检验法检验结果高于拉网式检验法,差异有统计学意义(P<0.05);分级检验法TC、TG、HDL-C与拉网式检验法阳性检出率比较,差异无统计学意义(P>0.05),LDL-C、ApoAI、ApoB分级检验法阳性检出率高于拉网式检验法,差异有统计学意义(P<0.05);且分级检验法漏检率(1.11%)低于拉网式(18.33%),差异有统计学意义(P<0.05)。结论常规拉网式检验方法和分级检验方法各有优势,但在血脂生化检验工作中,分级检验方法可以提高检验的准确率以及阳性检测率,能够降低漏检率,值得在临床推广和使用。
Objective To investigate the effects of two different test methods,i.e.,grading test method and conventional trawl test method,on serum lipid-related indexes.Methods 360 elderly people(aged 60 to 80 years old,including 198 males and 162 females)who were tested for serum lipid in Lilian community from May to June 2018 were randomly divided into the grading test group[n=180,including 97 males and 83 females,with an average age of(73.51±0.34)years]and the conventional trawl test group[n=180,including 101 males and 79 females,with an average age of(72.71±0.41)years].There was no significant difference in gender and age between the two groups of personnel being tested(P<0.05).The two groups of personnel being tested were respectively tested for six indexes of total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein AI(ApoAI),and apolipoprotein B(ApoB)by using the grading test method and conventional trawl test method.The data such as test results,positive detection rate,missed detection rate,etc.of the two test methods were analyzed to compare the effects of the two different test methods on serum lipid-related indexes.Results The test results of TC,TG,HDL-C,LDL-C,ApoAI and ApoB of the grading test method were higher than those of the trawl test method,with statistically significant difference(P<0.05);There was no statistically significant difference in the positive detection rates of TC,TG and HDL-C between the grading test method and the trawl test method(P>0.05);The positive detection rates of LDL-C,ApoAI and ApoB of the grading test method were higher than those of the trawl test method,with statistically significant difference(P<0.05);And the missed detection rate of the grading test method(1.11%)was lower than that of the trawl test method(18.33%),with statistically significant difference(P<0.05).Conclusion Both the conventional trawl test method and the grading test method have their own advantages.However,in the biochemical test of serum lipid,the grading test method can improve the accuracy of the test and the positive detection rate,and can reduce the missed detection rate,which is worthy of clinical promotion and use.
作者
郭菁
甄英鹏
GUO Jing;ZHEN Yingpeng(Department of Laboratory Medicine,Nangang Hospital of Guangzhou Development District Hospital,Guangdong,Guangzhou 510762,China)
出处
《中国医药科学》
2020年第13期151-154,共4页
China Medicine And Pharmacy
关键词
分级检验方法
拉网式检验方法
血脂指标
阳性检出率
Grading test method
Trawl test method
Serum lipid indexes
Positive detection rate
