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克罗恩病病因病机探析 被引量:27

Etiology and Pathogenesis of Crohn’s Disease in Traditional Chinese Medicine
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摘要 提出克罗恩病可从肠痈论治,将克罗恩病的病因归纳为外感六淫疫毒之邪、情志失调、饮食不节、久病体虚等,其发病主要以湿热蕴结为由,以瘀血阻滞为标,以脾肾亏虚为本,以痰瘀互结为变。克罗恩病多属本虚标实、虚实夹杂之证,在对该病本虚的认识基础上,更应重视湿、热、痰、瘀在疾病发生发展过程中的作用。治疗时应紧抓病因病机,早期以清热利湿、活血散瘀、疏理气机为主,后期在祛痰化瘀的基础上注重健脾益气扶正、补脾益肾固本。 It is suggested that Crohn’s disease can be treated from intestinal carbuncle,and the etiology of Crohn’s disease can be summarized as follows:external contraction of six pathogenic factors and epidemic toxins,emotional disorders,poor diet,chronic disease with physical deficiency,etc.Crohn’s disease is mainly caused by dampness and heat accumulation,blood stasis obstruction as the branch,spleen and kidney deficiency as the root,combined phlegm and blood stasis as the conversion.Crohn’s disease is the syndrome of deficiency in root and excess in branch,deficiency-excess in complexity.Based on the understanding of deficiency in root of Crohn’s disease,more attention should be paid to the role of dampness,heat,phlegm and blood stasis in the occurrence and development of the disease.In the treatment,we should grasp the etiology and pathogenesis.In the early stage,clearing heat and draining dampness,activating blood and resolving stasis,and regulating qi are mainly used.In the advanced stage,invigorating spleen,replenishing qi and reinforcing healthy qi,tonifying spleen,replenishing kidney and consolidating root are emphasized based on removing phlegm and resolving stasis.
作者 栗梦晓 赵文霞 LI Mengxiao;ZHAO Wenxia(Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China;The First Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou 450008,China)
出处 《山东中医药大学学报》 2020年第4期396-399,共4页 Journal of Shandong University of Traditional Chinese Medicine
基金 河南省自然科学基金资助项目(编号:162300410183)。
关键词 克罗恩病 六淫疫毒 情志失调 饮食不节 久病体虚 湿热蕴结 瘀血阻滞 脾肾亏虚 痰瘀互结 Crohn’s disease six pathogenic factors and epidemic toxins emotional disorders poor diet chronic disease with physical deficiency dampness and heat accumulation blood stasis obstruction deficiency of spleen and kidney combined phlegm and blood stasis
作者简介 栗梦晓(1994-),女,河南郑州人,2017年级硕士研究生,研究方向:中医药防治消化系统疾病。电话:15290858328,邮箱:944941787@qq.com;通信作者:赵文霞(1956-),女,河南驻马店人,主任医师,医学博士,博士研究生导师,主要从事中医药防治消化系统疾病研究。电话:13703958960,邮箱:634571068@qq.com。
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