摘要
目的探讨百草枯中毒患者早期胸部CT表现及对患者临床预后的影响。方法选取2012年1月至2019年11月本院收治的百草枯中毒患者50例为研究对象,分为死亡组和生存组,每组25例。两组患者均进行胸部CT检查,观察服用剂量对患者胸部损害程度以及存活率并对其进行评估。结果生存组早期CT值、中期CT增加值以及中期肺部损伤范围扩大指标均低于死亡组(P<0.05)。生存组服用剂量≤10 mL 12例,死亡组8例,死亡率为32.0%;生存组服用剂量10~30 mL 12例,死亡组9例,死亡率为36.0%;生存组服用剂量≥30 mL 1例,死亡组8例,死亡率32.0%;生存组肺纹理增多10例,胸膜下线8例,胸膜增厚7例,肺过度充气6例,支气管扩张3例,胸腔积液8例;死亡组肺纹理增多22例,胸膜下线21例,胸膜增厚18例,肺过度充气16例,支气管扩张8例,胸腔积液16例。结论早期胸部CT表现可以有效的帮助主治医师更好的了解患者的情况、中毒后患者的胸部损害部位、程度以及服用剂量与死亡率的关系等,从而给出具有针对性的治疗方案,提高患者的生存率,在临床上具有重要的意义。
Objective To investigate the effect of early chest CT on patients with paraquat poisoning and its clinical prognosis.Methods A total of 50 patients with paraquat poisoning admitted to our hospital from January 2012 to November 2019 to were selected as study subjects.They were divided into death group and survival group,with 25 cases in each group.Chest CT scans were performed in both groups to observe and assess the extent of chest damage and survival.Results The early CT value,the mid-term CT increase,and the expansion index of the mid-stage lung injury were lower in the survival group than in the death group(P<0.05).12 patients received dose≤10 mL in the survival group and 8 patients in the death group,with a mortality rate of 32.0%.There were 12 patients in the survival group and 9 patients in the death group,with a mortality rate of 36.0%.In the survival group,1 patient received dose≥30 mL.In the death group,8 patients received dose≥30 mL.The mortality rate was 32.0%.10 cases of lung texture,8 cases of pleural line,7 cases of pleural thickening,and 6 cases of pulmonary hyperinflation.There were 3 cases of bronchiectasis and 8 cases of pleural effusion in the survival group.22 cases of lung texture increased,21 cases of pleural line,18 cases of pleural thickening,16 cases of pulmonary hyperinflation,8 cases of bronchiectasis and 16 cases of pleural effusion in the death group.Conclusion Early chest CT findings can effectively help the attending physician better understand the patient's condition,and have a more detailed understanding of the location and extent of chest damage and the relationship between dose and mortality after poisoning,so that it can be given targeted treatment programs can improve the survival rate of patients and have important clinical significance.
作者
胡碧华
曹子文
陈丽琨
周建中
伍健芝
Hu Bihua;Cao Ziwen;Chen Likun;Zhou Jianzhong;Wu Jianzhi(Department of Radiology,Occupational Health Care Center,Guangdong Occupational Disease Prevention Hospital,Guangzhou,Guangdong,510300,China)
出处
《当代医学》
2020年第19期86-89,共4页
Contemporary Medicine
