摘要
目的探讨宫腔镜联合左炔诺酮宫内缓释系统(LNG-IUS)治疗慢性肾功能不全伴异常子宫出血(AUB)患者的临床疗效。方法宫腔镜术及术后联用LNG-IUS治疗慢性肾功能不全伴AUB患者56例,比较宫腔镜前后对患者血肌酐及血红蛋白的影响,比较宫腔镜术前和LNG-IUS放置术后6月患者的月经量、子宫内膜厚度、血红蛋白及LNG-IUS放置术后的随访情况和不良反应的发生率。结果宫腔镜术前、术后患者的血肌酐水平和血红蛋白比较差异无统计学意义(P>0.05),宫腔镜术前患者的月经量、子宫内膜厚度、血红蛋白与LNG-IUS放置术后6个月比较均有差异有统计学意义(P<0.01);随LNG-IUS放置术后时间的延长,术后1、3、6、12个月患者的月经量、子宫内膜厚度较前降低、血红蛋白较术前提高,术后1年不良反应的发生率为19.64%。结论慢性肾脏病处于何期,宫腔镜治疗对患者的肾功能和血红蛋白均无影响,宫腔镜辅助左炔诺酮缓释系统治疗慢性肾功能不全伴AUB安全有效。
Objective To evaluate the effectiveness of patients with chronic renal failure combined abnormal uterine bleeding by hysteroscopy and intrauterine device.Methods 56 cases of chronic renal failure combined abnormal uterine bleeding by hysteroscopy and intrauterine device were enrolled in hospital.The effects of before and after hysteroscopy on serum creatinine and hemoglobin were compared.The menstrual volume,endometrial thickness and hemochrome of patients before hysteroscopy and 6 months after LNG-IUS placement were compared.Followup situation of Intrauterine devic was placed and incidence of adverse reactionsr LNG-IUS was placed after 1 year.Results There was no statistical difference in serum creatinine and hemoglobin before and after hysteroscopy(P>0.05).In menstrual volume,endometrial thickness,hemochrome before hysteroscopy and LNG-IUS which was placed after 6 months were statistically significant difference(P<0.01).After LNGIUS was placed about 1,3,6,12 months,the menses,endometrial thickness of patients were lower than before,hemoglobin of patient was higher than before.The incidence of adverse reactions ofLNG-IUS which was placed was 19.64%after 1 year.Conclusion Hysteroscopy has no effect on renal function and hemochrome when chronic kidney disease is in any stage,patients with chronic renal failure combined abnormal uterine bleeding by hysteroscopy and Intrauterine device are effective and safe.
出处
《浙江临床医学》
2020年第5期696-697,700,共3页
Zhejiang Clinical Medical Journal
关键词
AUB
慢性肾功能不全
宫腔镜
左炔诺酮宫内缓释系统
Abnormal uterine bleeding
Chronic renal insufficiency
Hysteroscopy
Intrauterine device
