摘要
目的评价真实世界舒血宁注射液使用的合理性和安全性。方法收集2017年5月至2018年4月北京市房山区某两家医院舒血宁注射液患者病例共计105份,利用临床用药合理性评价方法,从用药适宜性和药物利用指数两个维度研究评价了舒血宁注射液真实世界使用的合理性和安全性,为舒血宁注射液的临床合理用药提供依据。结果105例使用舒血宁注射液的患者中,给药剂量适宜性100%,输液溶媒适宜性65.71%,滴注速度适宜性6.67%,适应症适宜性68.57%,联合用药适宜性85.71%,并有1例患者输液后发生不良反应。dDUI=1,说明医师处方舒血宁注射液平均日剂量等于DDD,cDUI>1,说明医师处方舒血宁注射液平均日浓度大于DDC。结论本次真实世界研究,舒血宁注射液临床用药适宜性总体比值偏低,且存在超浓度给药,临床用药的合理性和安全性有待提高。
Objective To evaluate the rationality and safety of Shuxuening injection in the real world.Methods Collected in May 2017 to April 2018 Beijing Fangshan district two hospitals Shuxuening injection a total of 105 cases of patients, used the method of clinical medication rationality evaluation, from drug using suitability and drug utilization index of two dimensions researched and evaluated the Shuxuening injection using the rationality and security in the real world, To provide basis for clinical rational use of shuxuening injection.Results Among the 105 patients of using Shuxuening injection, Dose suitability was 100 %, infusion solvent suitability 65.71 %, infusion speed suitability 6.67 %, Indications suitability was 68.57%, combination drug suitability 85.71%. And 1 patient had adverse reactions after infusion. dDUI=1, indicating that the average daily dose of Shuxuening injection in the doctor’s prescriptions is equal to DDD, cDUI>1, indicating that the average daily concentration of Shuxuening injection in the doctor’s prescriptions is greater than DDC.Conclusion In this real world study, the overall ratio of clinical drug suitability of Shuxuening injection is low, and there is overconcentration drug administration. The rationality and safety of clinical drug use need to be improved.
作者
王蕾
朱斌
马欣原
田晓娜
朱振宇
WANG Lei;ZHU Bin;MA Xin-yuan;TIAN Xiao-na;ZHU Zhen-yu(Beijing Fangshan District Maternity Hospital,Beijing 100000,China;不详)
出处
《医药论坛杂志》
2020年第4期5-8,共4页
Journal of Medical Forum
基金
国家药典委员会(2-847-17-DR)。
关键词
舒血宁注射液
用药合理性和安全性
药物利用指数
Shuxuening injection
Medication rationality and safety
Drug utilization index
