摘要
目的:探讨胃癌肿瘤部位与胃癌患者预后之间的关系。方法:收集手术治疗的胃癌患者共2141例。按照肿瘤发生部位将胃癌分为胃底贲门、胃体、胃窦幽门三组,其中肿瘤位于胃底贲门为A组,位于胃体为B组,位于胃窦幽门为C组。观察每组中患者人数、性别、年龄、肿瘤大小、病理类型、术后出现转移及5年生存率之间的关系。结果:在2141例患者中,男1642例,女499例。年龄方面比较:A组患者平均年龄为(60.59±9.28)岁,B组平均年龄为(55.88±11.34)岁,C组平均年龄为(55.37±11.75)岁。肿瘤大小比较:A组患者中肿瘤直径平均为(5.11±2.17)cm,B组中肿瘤直径平均为(6.13±2.99)cm,C组中肿瘤直径平均为(4.37±2.31cm)。肿瘤病理则以腺癌及多种病理类型混合的肿瘤居多。术后出现转移方面:A组中术后出现转移的共有170例,无转移359例,B组中出现转移的246例,无转移491例,C组中出现转移的240例,无转移635例。患者5年存活方面,A组中共存活261例(49.34%),死亡268例(50.66%),B组中共存活323例(43.83%),死亡414例(56.17%),C组中存活496例(56.69%),死亡379例(43.31%)。总生存期方面:A组患者为(40.78±22.05)月,B组为(36.44±23.63)月,C组为(42.69±22.16)月。结论:三组患者在性别、年龄、肿瘤大小、术后出现转移及预后之间比较均有统计学差异,而三组间在病理类型上比较则无统计学差异。胃癌发生的部位不同其预后亦不同。胃窦幽门癌患者预后最好,胃底贲门部胃癌预后次之,胃体部癌肿预后最差。
Objective:To investigate the relationship between tumor location and prognosis of gastric cancer patients.Methods:A total of 2141 gastric cancer patients treated with operation were collected and divided into group A(gastric fundus),group B(gastric body)and group C(gastric antrum).The differences in the number of patients,gender,age,tumor size,pathological type,postoperative metastasis,and 5-year survival rate in each group were observed.Results:Among 2141 patients,there were 1642 males and 499 females.The average age of group A was(60.59±9.28)years,group B was(55.88±11.34)years,and group C was(55.37±11.75)years.The average tumor diameter in group A was(5.11±2.17)cm,in group B was(6.13±2.99)cm,and in group C was(4.37±2.31 cm).The majority of tumor pathology were adenocarcinoma and mixed tumor types.There were 170 cases of metastasis in group A and 359 cases without metastasis,246 cases in group B and 491 cases without metastasis,240 cases in group C and 635 cases without metastasis.In terms of 5-year survival,261 cases(49.34%)survived in group A and 268 cases(50.66%)died,323 cases(43.83%)survived in group B and 414 cases(56.17%)died,496 cases(56.69%)survived in group C and 379 cases(43.31%)died.The total survival time was(40.78±22.05)months in group A,(36.44±23.63)months in group B and(42.69±22.16)months in group C.Conclusion:There were significant differences in gender,age,tumor size,postoperative metastasis and prognosis among the three groups,but there was no significant difference in pathological types among the three groups.The prognosis of gastriccancer varies with the location.The prognosis of gastric body cancer is the worst,the prognosis of gastric pylorus cancer is the best,the prognosis of gastric fundus cancer is between the two.
出处
《陕西医学杂志》
CAS
2020年第5期626-629,共4页
Shaanxi Medical Journal
基金
国家重点研发计划项目子课题(2017YFC1311002,2017YFC1311004)。
关键词
胃癌
肿瘤部位
生存期
肿瘤大小
病理类型
预后
Gastric cancer
Tumor location
Survival time
Tumor size
Pathological type
Prognosis
作者简介
通讯作者:杨鹏。
