摘要
目的:调查肾移植受者免疫抑制药物依从性的现况并分析其影响因素。方法:采用一般情况调查表和免疫抑制药物依从性Basel评估量表对肾移植受者进行多中心横断面调查。结果:共纳入819例肾移植受者,免疫抑制药物依从性差的发生率为43.8%,其中不按时服药最常发生,其次是漏服药。免疫抑制药物依从性的独立影响因素包括移植时间、器官来源、术后是否存在并发症和透析时间。结论:目前肾移植受者的免疫抑制药物依从率较低,尤其是移植时间长、活体供肾、有并发症以及透析时间短的受者,医务人员在随访过程中应重视该人群依从性的筛查,帮助肾移植受者进行疾病和药物的管理。
Objective:The purpose of the study was to assess the influencing factors associated with medication adherence related to immunosuppressive treatment in patients who underwent kidney transplant in China,therefore to provide evidence for clinical interventions to improve adherence.Methods:Following a multi-center cross-sectional approach,a self-designed demographic information questionnaire and the Basel Assessment of Adherence with Immunosuppressive Medication Scale were used to collect information from the recipients who underwent kidney transplant for more than 3 months.Results:A convenient sample of 819 patients with kidney transplant were included in the study,of which 359 were classified as non-adherent(43.8%).Among them,the most frequently reported event related to non-adherent was not taking medication on time,followed by missed medication taking.The independent influencing factors of medication adherence to immunosuppressive treatment were the length of time after kidney transplant,donor type,complications after kidney transplant,and the duration of dialysis.Conclusion:The medication adherence to immunosuppressive treatment among patients with kidney transplant is relatively low.Patients with a longer post-transplant years,living donor,having complications and with shorter duration of dialysis should receive more attention in adherence screening,therefore to assist them with medication management in the follow up period.
作者
王莎莎
刘红霞
高凤莉
张小东
付迎欣
赵杰
于立新
苗芸
叶桂荣
WANG Shasha;LIU Hongxia;GAO Fengli;ZHANG Xiaodong;FU Yingxin;ZHAO Jie;YU Lixin;MIAO Yun;YE Guirong(School of Nursing,Beijing University of Chinese Medicine,Beijing,102488,China)
出处
《中国护理管理》
CSCD
北大核心
2020年第3期354-359,共6页
Chinese Nursing Management
基金
国家自然科学基金面上项目(81572235)。
关键词
肾移植
受者
服药依从性
kidney transplant
recipients
medication adherence
作者简介
王莎莎,硕士在读;通信作者:刘红霞,博士,教授,E-mail:hongxia_t@163.com。
