摘要
以Ti粉和Ni粉为原料,对粉末进行预处理后,采用限空间自蔓延工艺制备多孔NiTi合金,对合金的孔隙结构、物相和超弹性等性能进行表征,进一步通过体外细胞毒性试验(MTT法)评价合金的生物安全性能。结果表明:粉末未进行预处理时,难以获得孔隙结构理想的多孔合金。对粉末进行适当的预处理后,可以获得综合性能优异的多孔NiTi合金。合金中的孔隙分布均匀,孔隙形状近球形,孔隙率为34%,孔径为100~500μm。合金物相由单一的B2相组成,具有良好的超弹性,在2.5%和4.0%应变下经过3次循环加载-卸载压缩测试,未产生残余应变。2种应变时对应的抗压强度分别为250和363 MPa,弹性模量为15.4 GPa。MTT试验显示细胞形态体征正常,细胞毒性为1级,表明制备的多孔NiTi合金具有良好的生物安全性能。
A newly designed space-controlled self-propagating synthesis process was used to prepare porous Ni Ti shape memory alloys(SMAs) after the pretreatment of Ti powder and Ni powder. Properties including pore structures, phase composition and superelasticity of the alloys were characterized, and the biological safety was evaluated by in vitro cytotoxicity test(MTT). The results show that it is difficult to obtain SMAs with ideal pore structures without pretreating the mixed powders. After pretreating the raw powders properly, SMAs with excellent comprehensive properties can be fabricated. Nearly spherical pores with 34% porosity and diameters between 100 ~500 μm are homogeneously distributed in the alloys. The alloys are composed of single B2 and have good superelasticity. After three cyclic loading and unloading compression tests at the strains of 2.5% and 4.0%, no residual strain is generated. The corresponding compressive strength is 250 and 363 MPa, respectively, and the elastic modulus is 15.4 GPa. MTT tests show morphologies of cells in SMAs leaching solution are normal and the cytotoxicity is estimated level 1, indicating SMAs have good biological safety.
作者
陈峰
闫志巧
施麒
刘咏
刘彬
Chen Feng;Yan Zhiqiao;Shi Qi;Liu Yong;Liu Bin(Guangdong Institute of Materials and Processing,Guangdong Academy of Sciences,Guangzhou 510650,China;Central South University,Changsha 410083.China;Engineering Research Center for Powder Metallurgy of Titanium&Rare Metals,Guangzhou 510650,China)
出处
《稀有金属材料与工程》
SCIE
EI
CAS
CSCD
北大核心
2020年第3期1009-1014,共6页
Rare Metal Materials and Engineering
基金
国家自然科学基金(51404077)
广东省自然科学基金(2015A030313775)
广东省科学院实施创新驱动发展能力建设专项(2019GDASYL-0402006,2018GDASCX-0117)
广东省公益研究与能力建设项目(2017A070701029)
广东省重点领域研发计划项目(2018B090904004)
广州市科技计划项目(ZWY201704003,201508030032)。
关键词
多孔NITI合金
限空间自蔓延
超弹性
细胞毒性
porous NiTi alloys
space-controlled self-propagating
superelasticity
cytotoxicity
作者简介
陈峰,男,1979年生,博士生,高级工程师,广东省科学院广东省材料与加工研究所,广东广州510650,电话:020-61086127,E-mail:chenfengcsu@163.com。
