摘要
静脉血栓栓塞(VTE)是炎症性肠病(IBD)公认的肠外表现,发病率和死亡率均较高。IBD血栓栓塞的机制尚不完全清楚,涉及多种获得性和遗传性因素。目前主要指南推荐给予IBD患者机械或药物治疗以预防血栓栓塞,但临床上尚未广泛应用。本文就IBD血栓栓塞的机制作一综述。
Venous thromboembolism(VTE)is considered as an extraintestinal manifestation of inflammatory bowel disease(IBD)and with high morbidity and mortality.The pathogenesis of VTE in IBD is not fully clear yet,however,multiple acquired and inherited factors have been implicated.Mechanical and pharmacological prophylaxis are recommended by the leading guidelines for preventing VTE in patients with IBD.However,it is not widely applied in clinic.This article reviewed the mechanism of VTE in IBD.
作者
雷玉英
黄华
路明亮
刘嘉
蒋明远
林凡榆
LEI Yuying;HUANG Hua;LU Mingliang;LIU Jia;JIANG Mingyuan;LIN Fanyu(Department of Gastroenterology,the Second Affiliated Hospital of Kunming Medical University,Kunming,650101)
出处
《胃肠病学》
2020年第1期59-62,共4页
Chinese Journal of Gastroenterology
基金
云南省应用基础研究(2017FE467)。
关键词
炎症性肠病
静脉血栓形成
机制
Inflammatory Bowel Disease
Venous Thrombosis
Mechanisms
作者简介
通信作者:黄华,Email:hhtrq@163.com。