摘要
目的探究地佐辛复合丙泊酚对全麻手术患者术后镇痛及苏醒期躁动的影响。方法选择2017年1月~2019年1月在我院接受治疗的60例全麻手术患者进行研究。按照随机数字表法将其分为对照组和研究组,每组30例。手术结束前15 min,对照组静脉注射丙泊酚1 mg/kg+芬太尼0.6μg/kg,研究组静脉注射丙泊酚1 mg/kg+地佐辛0.15 mg/kg。比较两组患者从术后到意识清醒的时间(T1)和移除导管后20 min(T2)的疼痛评分,苏醒期躁动程度以及不良反应总发生率。结果T2期间研究组患者的疼痛评分低于对照组,差异有统计学意义(P<0.05)。两组T2期间的疼痛评分低于T1期间,差异有统计学意义(P<0.05)。研究组患者苏醒期的躁动率(6.67%)低于对照组(46.67%),差异有统计学意义(P<0.05)。研究组患者苏醒期不良反应总发生率(6.67%)低于对照组(36.67%),差异有统计学意义(P<0.05)。结论对全麻手术患者使用地佐辛复合丙泊酚可以明显降低患者术后疼痛、躁动反应,并且可以有效降低不良反应的发生率,在临床上值得广泛使用。
Objective To explore the effect of Dizocine combined with Propofol on postoperative analgesia and agitation during recovery in patients undergoing general anesthesia.Methods A total of 60 patients undergoing general anesthesia in our hospital from January 2017 to January 2019 were selected for study.According to the random number table method,they were divided into control group and study group,with 30 cases in each group.The control group received intravenous Fentanyl 0.6 g/kg+Propofol 1 mg/kg,and the study group received intravenous Propofol 1 mg/kg+Dizocine 0.15 mg/kg.The pain scores of the two groups from postoperative to conscious time(T1)and 20 min after catheter removal(T2),restlessness and incidence of adverse reactions during recovery were compared.Results During T2,the pain score of patients in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The pain scores of the two groups at T2 were lower than those at T1,and the differences were statistically significant(P<0.05).The agitation rate of patients in the study group(6.67%)was lower than that of patients in the control group(46.67%),and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the awakening period in the study group(6.67%)was lower than that in the control group(36.67%),and the difference was statistically significant(P<0.05).Conclusion The use of Dizocine combined with Propofol in patients undergoing general anesthesia can significantly reduce postoperative pain and agitation,and it also can effectively reduce the incidence of adverse reactions,which is worthy of extensive use in clinical practice.
作者
李小莉
LI Xiao-li(Department of Anesthesiology,the Fourth Affiliated Hospital of Nanchang University,Jiangxi Province,Nanchang 330000,China)
出处
《中国当代医药》
2020年第9期104-106,共3页
China Modern Medicine
关键词
地佐辛
丙泊酚
镇痛
苏醒期躁动
Dizocine
Propofol
Analgesia
Waking agitation
作者简介
李小莉(1985-),女,本科,主治医师,研究方向:临床麻醉。
